Introduction：Basic information about CAS 172616-80-7|IR820, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | IR820 |
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| CAS Number | 172616-80-7 | Molecular Weight | 849.47200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C46H50ClN2NaO6S2 | Melting Point | >300ºC |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | New Indocyanine Green |
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| Synonym | More Synonyms |
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IR820 BiologicalActivity
| Description | IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| In Vitro | Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 体内[1]： 1. 将粉末状的 IR-820 与磷酸盐缓冲液 (PBS) 新鲜混合至终浓度为 0.2 mM，取 100 μL 此溶液注射到实验动物中。 2.使用 2 组四只无毛 SKHi/sKHl 小鼠。 第一组通过静脉尾静脉注射 IR-820，而第二组通过腹膜内注射。 3. IR-820 的最大激发和发射波长分别为 710 nm 和 820 nm。 两组连续成像 8 天。 |
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| References | [1]. Suresh I Prajapati, et al. Near-infrared imaging of injured tissue in living subjects using IR-820. Mol Imaging. 2009 Jan-Feb;8(1):45-54. |
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Chemical & Physical Properties
| Melting Point | >300ºC |
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| Molecular Formula | C46H50ClN2NaO6S2 |
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| Molecular Weight | 849.47200 |
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| Exact Mass | 848.27000 |
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| PSA | 137.41000 |
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| LogP | 12.04650 |
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| InChIKey | RANIQVAJHXBIAY-UHFFFAOYSA-M |
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| SMILES | CC1(C)C(=CC=C2CCCC(C=CC3=[N+](CCCCS(=O)(=O)[O-])c4ccc5ccccc5c4C3(C)C)=C2Cl)N(CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21.[Na+] |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| IR-820,2-[2-[2-Chloro-3-[[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benzo[e]indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benzo[e]indolium hydroxide inne |
| 2-(2-(2-Chloro-3-((1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benzo[e]indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl] |
| New indocyanine Green |
| IR-820 |
| 2-[2-[2-Chloro-3-[[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benzo[e]indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benzo(e)indolium hydroxide,inner salt |
| 2-[2-[2-chloro-3-[[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2h-benzo[e]indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,1-dimethyl-3-(4-sulfobutyl)-1h-benzo[e]indolium hydroxide inner salt,sodium salt |
| MFCD04038859 |
| IR820 |
