CAS 623-91-6|Diethyl fumarate
Introduction：Basic information about CAS 623-91-6|Diethyl fumarate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Diethyl fumarate | ||
|---|---|---|---|
| CAS Number | 623-91-6 | Molecular Weight | 172.178 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 214.0±0.0 °C at 760 mmHg |
| Molecular Formula | C8H12O4 | Melting Point | 41641ºC |
| MSDS | ChineseUSA | Flash Point | 93.3±0.0 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | diethyl fumarate |
|---|---|
| Synonym | More Synonyms |
Diethyl fumarate BiologicalActivity
| Description | Diethyl fumarate is an endogenous metabolite. |
|---|---|
| Related Catalog | Research Areas >>Metabolic Disease |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 214.0±0.0 °C at 760 mmHg |
| Melting Point | 41641ºC |
| Molecular Formula | C8H12O4 |
| Molecular Weight | 172.178 |
| Flash Point | 93.3±0.0 °C |
| Exact Mass | 172.073563 |
| PSA | 52.60000 |
| LogP | 1.68 |
| Vapour Pressure | 0.2±0.4 mmHg at 25°C |
| Index of Refraction | 1.443 |
| InChIKey | IEPRKVQEAMIZSS-AATRIKPKSA-N |
| SMILES | CCOC(=O)C=CC(=O)OCC |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, acids, bases, reducing agents. |
| Water Solubility | immiscible |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1780 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81805 No. of Facilities: 367 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 1350 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22 |
| Safety Phrases | S23 |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | 3 |
| RTECS | EM5950000 |
| HS Code | 29171990 |
Customs
| HS Code | 2917190090 |
|---|---|
| Summary | 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Articles26
More Articles| Fumarate analogs act as allosteric inhibitors of the human mitochondrial NAD(P)+-dependent malic enzyme. PLoS ONE 9(6) , e98385, (2014) Human mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME) is allosterically activated by the four-carbon trans dicarboxylic acid, fumarate. Previous studies have suggested that the dicarboxylic... | |
| Kinetics of poly(propylene fumarate) synthesis by step polymerization of diethyl fumarate and propylene glycol using zinc chloride as a catalyst. J. Biomater. Sci. Polym. Ed. 13(1) , 95-108, (2002) Diethyl fumarate and propylene glycol were reacted in the presence of a zinc chloride catalyst to synthesize poly(propylene fumarate) (PPF) over a period of 12 hours. The kinetics of the transesterifi... | |
| Facile preparation of the tosylhydrazone derivatives of a series of racemic trans-3,4-substituted cyclopentanones. Molecules 17(1) , 1-14, (2011) We report the synthesis and characterization of a variety of trans-3,4-substituted cyclopentanones and the corresponding tosylhydrazone derivatives starting with diethyl fumarate. Protection of the ke... |
Synonyms
| 2-Butenedioic acid(2E)-, 1,4-diethyl ester |
| 2-Butenedioic acid, diethyl ester, (2E)- |
| Diethyl-(2E)-but-2-endioat |
| EINECS 210-819-7 |
| Diethyl (2E)-but-2-enedioate |
| Diethyl (2E)-2-butenedioate |
| Fumaric acid, diethyl ester (8CI) |
| Diethyl fumarate |
| MFCD00064455 |
| Diethyl maleate |
