CAS 90921-11-2|anemonin

Introduction：Basic information about CAS 90921-11-2|anemonin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. anemonin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	anemonin
CAS Number	90921-11-2	Molecular Weight	192.17
Density	1.45±0.1 g/cm3 (20 ºC 760 Torr)	Boiling Point	/
Molecular Formula	C₁₀H₈O₄	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	1,7-Dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione
Synonym	More Synonyms

anemonin BiologicalActivity

Description	(Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases[1][2].
Related Catalog	Signaling Pathways >>Epigenetics >>PKCSignaling Pathways >>Immunology/Inflammation >>NO SynthaseResearch Areas >>Inflammation/ImmunologySignaling Pathways >>TGF-beta/Smad >>PKC
References	[1]. Jiang L, et al. Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ. Chin Med. 2022 Mar 28;17(1):39. [2]. Lee TH, et al. Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor. J Ethnopharmacol. 2008 Mar 28;116(3):518-27.

Description

(Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases[1][2].

Related Catalog

Signaling Pathways >>Epigenetics >>PKCSignaling Pathways >>Immunology/Inflammation >>NO SynthaseResearch Areas >>Inflammation/ImmunologySignaling Pathways >>TGF-beta/Smad >>PKC

References

[1]. Jiang L, et al. Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ. Chin Med. 2022 Mar 28;17(1):39.

[2]. Lee TH, et al. Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor. J Ethnopharmacol. 2008 Mar 28;116(3):518-27.

Chemical & Physical Properties

Density	1.45±0.1 g/cm3 (20 ºC 760 Torr)
Molecular Formula	C₁₀H₈O₄
Molecular Weight	192.17
Exact Mass	192.04200
PSA	52.60000
LogP	0.48380
InChIKey	JLUQTCXCAFSSLD-UHFFFAOYSA-N
SMILES	O=C1C=CC2(CCC23C=CC(=O)O3)O1

Safety Information

HS Code	2932999099

Customs

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

protoanemonin

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