CAS 811442-84-9|Boc-NH-PEG4-CH2CH2NH2

Introduction:Basic information about CAS 811442-84-9|Boc-NH-PEG4-CH2CH2NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBoc-NH-PEG4-CH2CH2NH2
CAS Number811442-84-9Molecular Weight336.42400
Density1.059Boiling Point/
Molecular FormulaC15H32N2O6Melting Point/
MSDS/Flash Point222 °C

Names

Nametert-Butyl (14-amino-3,6,9,12-tetraoxatetradecyl)carbamate
SynonymMore Synonyms

Boc-NH-PEG4-CH2CH2NH2 BiologicalActivity

DescriptionBoc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker
Target

Cleavable

In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Hans-Georg Lerchen, et al. Preparation of antibody drug conjugates of kinesin spindle protein (KSP) inhibitors with anti-TWEAKR-antibodies. WO2016207094A1.

Chemical & Physical Properties

Density1.059
Molecular FormulaC15H32N2O6
Molecular Weight336.42400
Flash Point222 °C
Exact Mass336.22600
PSA101.27000
LogP1.62740
InChIKeyWCNWLERBLMBSOT-UHFFFAOYSA-N
SMILESCC(C)(C)OC(=O)NCCOCCOCCOCCOCCN

Safety Information

Hazard CodesXi
HS Code2924199090

Customs

HS Code2924199090
Summary2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

tert-butyl N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate
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