Introduction：Basic information about CAS 7437-55-0|8-Geranyloxypsoralen, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 8-Geranyloxypsoralen |
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| CAS Number | 7437-55-0 | Molecular Weight | 338.397 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 503.7±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O4 | Melting Point | / |
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| MSDS | USA | Flash Point | 258.4±30.1 °C |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 9-((3,7-Dimethylocta-2,6-dien-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one |
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| Synonym | More Synonyms |
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8-Geranyloxypsoralen BiologicalActivity
| Description | 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM[1]. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Cytochrome P450Research Areas >>Others |
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| Target | IC50: 3.93 μM (P450 3A4)[1] |
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| References | [1]. Row EC, et al. Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4. Bioorg Med Chem. 2006 Jun 1;14(11):3865-71. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 503.7±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O4 |
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| Molecular Weight | 338.397 |
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| Flash Point | 258.4±30.1 °C |
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| Exact Mass | 338.151794 |
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| PSA | 52.58000 |
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| LogP | 5.85 |
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| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
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| Index of Refraction | 1.583 |
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| InChIKey | SOVNCTNQAWWYAQ-OQLLNIDSSA-N |
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| SMILES | CC(C)=CCCC(C)=CCOc1c2occc2cc2ccc(=O)oc12 |
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| Storage condition | 2-8°C |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302-H317 |
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| Precautionary Statements | P280 |
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| Hazard Codes | Xn |
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| Risk Phrases | 22-43 |
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| Safety Phrases | 36-37 |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| 9-((3,7-Dimethylocta-2,6-dien-1-yl)-oxy)-7H-furo[3,2-g]chromen-7-one |
| 8-Geranyloxy psoralen |
| 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3,7-dimethyl-2,6-octadienyl)oxy)- |
| 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]- |
| 9-{[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one |
