Introduction：Basic information about CAS 141750-63-2|Pitavastatin lactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Pitavastatin lactone |
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| CAS Number | 141750-63-2 | Molecular Weight | 403.445 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 616.9±55.0 °C at 760 mmHg |
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| Molecular Formula | C25H22FNO3 | Melting Point | 92-95ºC |
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| MSDS | / | Flash Point | 326.9±31.5 °C |
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Names
| Name | Pitavastatin lactone |
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| Synonym | More Synonyms |
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Pitavastatin lactone BiologicalActivity
| Description | Pitavastatin lactone is a major metabolite of Pitavastatin in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes[1]. |
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| Related Catalog | Research Areas >>Cardiovascular Disease |
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| References | [1]. Fujino H, et al. Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization. Xenobiotica. 2003 Jan;33(1):27-41. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 616.9±55.0 °C at 760 mmHg |
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| Melting Point | 92-95ºC |
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| Molecular Formula | C25H22FNO3 |
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| Molecular Weight | 403.445 |
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| Flash Point | 326.9±31.5 °C |
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| Exact Mass | 403.158386 |
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| PSA | 59.42000 |
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| LogP | 3.44 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.721 |
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| InChIKey | XJVKVAFYQRWVAJ-MCBHFWOFSA-N |
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| SMILES | O=C1CC(O)CC(C=Cc2c(C3CC3)nc3ccccc3c2-c2ccc(F)cc2)O1 |
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Synonyms
| 2H-Pyran-2-one, 6-[(E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-, (4R,6S)- |
| (4R,6S)-6-{(E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]vinyl}-4-hydroxytetrahydro-2H-pyran-2-one |
| Pitavastatinlactone |
| Pitavastatin Impurity 4 |
