CAS 70018-51-8|Quazinone (Ro 13-6438)
Introduction：Basic information about CAS 70018-51-8|Quazinone (Ro 13-6438), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Quazinone (Ro 13-6438) | ||
|---|---|---|---|
| CAS Number | 70018-51-8 | Molecular Weight | 235.67000 |
| Density | 1.57g/cm3 | Boiling Point | 345.6ºC at 760 mmHg |
| Molecular Formula | C11H10ClN3O | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 162.8ºC |
Names
| Name | quazinone |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.57g/cm3 |
|---|---|
| Boiling Point | 345.6ºC at 760 mmHg |
| Molecular Formula | C11H10ClN3O |
| Molecular Weight | 235.67000 |
| Flash Point | 162.8ºC |
| Exact Mass | 235.05100 |
| PSA | 44.70000 |
| LogP | 1.36370 |
| Index of Refraction | 1.746 |
| InChIKey | BHZFZYLBVSWUMT-ZCFIWIBFSA-N |
| SMILES | CC1C(=O)NC2=Nc3cccc(Cl)c3CN21 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles21
More Articles| Phenotype-based screening of mechanistically annotated compounds in combination with gene expression and pathway analysis identifies candidate drug targets in a human squamous carcinoma cell model. J. Biomol. Screen. 11(5) , 457-68, (2006) The squamous cell carcinoma HeLa cell line and an epithelial cell line hTERT-RPE with a nonmalignant phenotype were interrogated for HeLa cell selectivity in response to 1267 annotated compounds repre... | |
| Role of cGMP-inhibited phosphodiesterase and sarcoplasmic calcium in mediating the increase in basal heart rate with nitric oxide donors. J. Mol. Cell. Cardiol. 32(10) , 1831-40, (2000) Nitric oxide (NO) donors increase heart rate (HR) through a guanylyl cyclase-dependent stimulation of the pacemaker current I(f), without affecting basal I(Ca-L). The activity of I(f)is known to be en... | |
| Relaxation of human ureteral smooth muscle in vitro by modulation of cyclic nucleotide-dependent pathways. Urol. Res. 28(2) , 110-5, (2000) Phosphodiesterases (PDE) are key enzymes regulating intracellular cyclic nucleotide turnover and, thus, smooth muscle tension. Recent reports have indicated the presence of PDE isoenzymes 1, 2, 4, and... |
Synonyms
| MFCD00211176 |
