CAS 70023-02-8|H-Gly-Asp-Asp-Asp-Asp-Lys-βNA ammonium salt

Introduction:Basic information about CAS 70023-02-8|H-Gly-Asp-Asp-Asp-Asp-Lys-βNA ammonium salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameH-Gly-Asp-Asp-Asp-Asp-Lys-βNA ammonium salt
CAS Number70023-02-8Molecular Weight788.76
Density1.468g/cm3Boiling Point1378.8ºC at 760 mmHg
Molecular FormulaC34H44N8O14Melting Point/
MSDSChineseUSAFlash Point787.7ºC
Symbol
GHS08
Signal WordWarning

Names

Name3-[(2-aminoacetyl)amino]-4-[[1-[[1-[[1-[[6-amino-1-(naphthalen-2-ylamino)-1-oxohexan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
SynonymMore Synonyms

BiologicalActivity

DescriptionGly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide (GD4K-na) is a substrate for human enteropeptidase (Km: 0.16 mM)[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro纯化的重组人肠肽酶轻链 (L-HEP) 以 Km: 0:16 mM 和 kcat: 115 秒的速率裂解 Gly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide[1]。
References

[1]. Gasparian ME, et al. Expression, purification, and characterization of human enteropeptidase catalytic subunit in Escherichia coli. Protein Expr Purif. 2003 Sep;31(1):133-9.  

Chemical & Physical Properties

Density1.468g/cm3
Boiling Point1378.8ºC at 760 mmHg
Molecular FormulaC34H44N8O14
Molecular Weight788.76
Flash Point787.7ºC
Exact Mass788.29800
PSA375.84000
LogP0.61690
Index of Refraction1.631
InChIKeyQLLWULMEPVZWTP-UHFFFAOYSA-N
SMILESNCCCCC(NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CN)C(=O)Nc1ccc2ccccc2c1
Storage condition−20°C

Safety Information

Symbol
GHS08
Signal WordWarning
Hazard StatementsH351
Precautionary StatementsP281
Personal Protective EquipmentEyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard CodesXn
Risk Phrases40
Safety Phrases22-36
RIDADRNONH for all modes of transport
WGK Germany3

Articles1

More Articles
The application of a new synthetic substrate to the determination of enteropeptidase in rat small intestine and human intestinal biopsies.

Clin. Chim. Acta 101 , 69, (1980)

The application of a new synthetic substrate to the direct determination of enteropeptidase is described. The substrate Gly-(L-Asp)4-L-Lys-2-naphthylamide contains the amino acid sequence of the activ...

Synonyms

MFCD00083712
H-Gly-Asp-Asp-Asp-Asp-Lys-βNA
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