CAS 22333-58-0|9-Hydroxy-alpha-lapachone

Introduction:Basic information about CAS 22333-58-0|9-Hydroxy-alpha-lapachone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name9-Hydroxy-alpha-lapachone
CAS Number22333-58-0Molecular Weight258.27
Density1.4±0.1 g/cm3Boiling Point436.4±45.0 °C at 760 mmHg
Molecular FormulaC15H14O4Melting Point/
MSDS/Flash Point166.4±22.2 °C

Names

Name9-hydroxy-2,2-dimethyl-3,4-dihydrobenzo[g]chromene-5,10-dione
SynonymMore Synonyms

9-Hydroxy-alpha-lapachone BiologicalActivity

Description9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC50 of 4.64 µM on LPS-induced NO production in RAW 264.7 cells[1].
Related CatalogSignaling Pathways >>Immunology/Inflammation >>NO SynthaseResearch Areas >>Inflammation/Immunology
References

[1]. Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5.  

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point436.4±45.0 °C at 760 mmHg
Molecular FormulaC15H14O4
Molecular Weight258.27
Flash Point166.4±22.2 °C
Exact Mass258.089203
PSA63.60000
LogP3.19
Vapour Pressure0.0±1.1 mmHg at 25°C
Index of Refraction1.624
InChIKeyMYROJYNCTNKRCD-UHFFFAOYSA-N
SMILESCC1(C)CCC2=C(O1)C(=O)c1c(O)cccc1C2=O

Safety Information

Hazard CodesXi
HS Code2914400090

Customs

HS Code2914400090
Summary2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Synonyms

9-Hydroxy-2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione
2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4-dihydro-9-hydroxy-2,2-dimethyl-
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CAS 35241-80-6|9-Methoxy-alpha-lapachone
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