CAS 112501-42-5|1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one

Introduction：Basic information about CAS 112501-42-5|1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one
CAS Number	112501-42-5	Molecular Weight	265.26
Density	1.4±0.1 g/cm3	Boiling Point	457.0±38.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₁NO₃	Melting Point	/
MSDS	/	Flash Point	230.2±26.8 °C

Names

Name	Piperolactam A
Synonym	More Synonyms

BiologicalActivity

Description	Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani[1].
Related Catalog	Research Areas >>Infection
Target	Leishmania
In Vitro	Piperolactam A 对杜氏利什曼原虫野生型、耐药和野外分离的无菌无鞭毛体细胞系具有抑制活性，IC50 值为 60 ± 9.6 μM (野生型)，分别为 121 ± 18 μM (抗 SSG)、109 ± 15 μM (抗 PMM) 和 87 ± 12 μM (野外分离株)[1]。
References	[1]. Bhattacharya P, et al. In Vitro susceptibilities of wild and drug resistant Leishmania donovani amastigotes to piperolactam A loaded hydroxypropyl-β-cyclodextrin nanoparticles. Acta Trop. 2016 Jun;158:97-106.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	457.0±38.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₁NO₃
Molecular Weight	265.26
Flash Point	230.2±26.8 °C
Exact Mass	265.073883
PSA	62.32000
LogP	2.34
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.776
InChIKey	KBGNBPGXVKPRQI-UHFFFAOYSA-N
SMILES	COc1cc2c3c(cc4ccccc4c3c1O)NC2=O

Safety Information

Hazard Codes	Xi

Synonyms

aristolactam FI

piperolactam-A

1-Hydroxy-2-methoxydibenzo[cd,f]indol-4(5H)-one

10-amino-4-hydroxy-3-methoxyphenanthrene-1-carboxylic acid lactam

Dibenz[cd,f]indol-4(5H)-one, 1-hydroxy-2-methoxy-

piperlactam A

Recommended......