Introduction：Basic information about CAS 937265-83-3|ARRY-380, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | ARRY-380 |
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| CAS Number | 937265-83-3 | Molecular Weight | 569.634 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C29H27N7O4S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine |
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| Synonym | More Synonyms |
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ARRY-380 BiologicalActivity
| Description | The product is the analog of ARRY-380, ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR |
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| Related Catalog | Research Areas >>Cancer |
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| References | [1]. ErbB-2 inhibitor ARRY-380 |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Molecular Formula | C29H27N7O4S |
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| Molecular Weight | 569.634 |
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| Exact Mass | 569.184509 |
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| PSA | 144.92000 |
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| LogP | 3.59 |
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| Index of Refraction | 1.709 |
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| InChIKey | QVMNYGOVNWWFKF-UHFFFAOYSA-N |
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| SMILES | Cc1cc(Nc2ncnc3ccc(-c4ccc(CNCCS(C)(=O)=O)o4)cc23)ccc1Oc1ccn2ncnc2c1 |
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| Storage condition | -20℃ |
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Synonyms
| HER2-Inhibitor-1 |
| UNII-H32S1659ED |
| CS-0484 |
| cc-595 |
| Arry-380 |
| ARRY-380 (analog ) |
