Introduction：Basic information about CAS 220941-93-5|CP-226269, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | CP-226269 |
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| CAS Number | 220941-93-5 | Molecular Weight | 310.37 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C18H19FN4 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole |
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| Synonym | More Synonyms |
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CP-226269 BiologicalActivity
| Description | CP 226269 is a potent dopamine D4 receptor agonist that induces calcium flux with EC50 of 32.0 nM. CP 226269 can be used in the research of schizophrenia and other related diseases[1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Dopamine ReceptorSignaling Pathways >>Neuronal Signaling >>Dopamine ReceptorResearch Areas >>Neurological Disease |
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| References | [1]. Robert B Moreland, et al. Comparative pharmacology of human dopamine D(2)-like receptor stable cell lines coupled to calcium flux through Galpha(qo5). Biochem Pharmacol. 2004 Aug 15;68(4):761-72. |
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Chemical & Physical Properties
| Molecular Formula | C18H19FN4 |
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| Molecular Weight | 310.37 |
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| Exact Mass | 310.15900 |
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| PSA | 35.16000 |
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| LogP | 3.02710 |
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| InChIKey | PQOIDBZLMJMYCD-UHFFFAOYSA-N |
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| SMILES | Fc1ccc2[nH]c(CN3CCN(c4ccccn4)CC3)cc2c1 |
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Safety Information
| RIDADR | NONH for all modes of transport |
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Synonyms
| HMS3263O08 |
| 5-fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1H-indole |
| 5-fluoro-2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1H-indole |
| 5-Fluoro-2-{[4-(2-pyridinyl)-1-piperazinyl]methyl}-1H-indole |
