CAS 606130-90-9|m-PEG4-azide

Introduction:Basic information about CAS 606130-90-9|m-PEG4-azide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namem-PEG4-azide
CAS Number606130-90-9Molecular Weight233.26500
Density/Boiling Point/
Molecular FormulaC9H19N3O4Melting Point/
MSDSChineseUSAFlash Point/
Symbol
GHS07
Signal WordWarning

Names

Name1-azido-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane
SynonymMore Synonyms

m-PEG4-azide BiologicalActivity

Descriptionm-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Belen Begines, et al. Synthesis of Reduction Sensitive Comb-Like Polyurethanes Using Click Chemistry. Journal of Polymer Science Part A: Polymer Chemistry, 2016, 54(24), 3888-3900.

Chemical & Physical Properties

Molecular FormulaC9H19N3O4
Molecular Weight233.26500
Exact Mass233.13800
PSA86.67000
LogP0.44566
Index of Refraction1.4500 to 1.4540
InChIKeyFFOZZVDSANUDAE-UHFFFAOYSA-N
SMILESCOCCOCCOCCOCCN=[N+]=[N-]
Storage condition2-8°C

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH302
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn
Risk Phrases22
RIDADRNONH for all modes of transport
HS Code29299090

Synonyms

AmbotzPEG1690
Me(OCH2CH2)4N3
O-(2-Azidoethyl)-O inverted exclamation marka-methyl-triethylene glycol
MeO-PEG4-Azide
1-azido-11-methoxy-3,6,9-trioxaundecane
1-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-2-methoxyethane
m-dPEG.(TM).4-azide
13-Azido-2,5,8,11-tetraoxatridecane
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