Introduction：Basic information about CAS 2980-32-7|Desmethylbellidifolin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Desmethylbellidifolin |
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| CAS Number | 2980-32-7 | Molecular Weight | 260.199 |
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| Density | 1.8±0.1 g/cm3 | Boiling Point | 605.6±55.0 °C at 760 mmHg |
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| Molecular Formula | C13H8O6 | Melting Point | 317ºC |
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| MSDS | / | Flash Point | 242.0±25.0 °C |
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Names
| Name | bellidin |
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| Synonym | More Synonyms |
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Desmethylbellidifolin BiologicalActivity
| Description | 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological Disease |
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| In Vitro | 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells[1]. |
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| In Vivo | 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm[1]. |
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| References | [1]. Ni Y, et al. Desmethylbellidifolin From Gentianella acuta Ameliorate TNBS-Induced Ulcerative Colitis Through Antispasmodic Effect and Anti-Inflammation. Front Pharmacol. 2019 Sep 20;10:1104. |
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Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
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| Boiling Point | 605.6±55.0 °C at 760 mmHg |
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| Melting Point | 317ºC |
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| Molecular Formula | C13H8O6 |
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| Molecular Weight | 260.199 |
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| Flash Point | 242.0±25.0 °C |
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| Exact Mass | 260.032074 |
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| PSA | 111.13000 |
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| LogP | 0.33 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.801 |
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| InChIKey | MPXAWSABMVLIBU-UHFFFAOYSA-N |
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| SMILES | O=c1c2c(O)cc(O)cc2oc2c(O)ccc(O)c12 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- ZD6122300
- CHEMICAL NAME :
- Xanthen-9-one, 1,3,5,8-tetrahydroxy-
- CAS REGISTRY NUMBER :
- 2980-32-7
- BEILSTEIN REFERENCE NO. :
- 0286545
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C13-H8-O6
- MOLECULAR WEIGHT :
- 260.21
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 20 ug/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 150,141,1985
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Synonyms
| Demethylbellidifolin |
| Xanthen-9-one,1,3,5,8-tetrahydroxy |
| Desmethylbellidifolin |
| Bellidin |
| norbellidifolin |
| 1,3,5,8-tetrahydroxyxanthone |
| Desmethybellidifolin |
| norbellidifodin |
| 1,3,5,8-Tetrahydroxy-9H-xanthen-9-one |
| 9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy- |
| 1,3,5,8-tetrahydroxy-xanthen-9-one |
| 1,3,5,8-tetrahydroxyxanthen-9-one |
