CAS 52187-80-1|Luteolin-3',7-di-O-glucoside

Introduction:Basic information about CAS 52187-80-1|Luteolin-3',7-di-O-glucoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameLuteolin-3',7-di-O-glucoside
CAS Number52187-80-1Molecular Weight610.51700
Density1.742 g/cm3Boiling Point998ºC at 760 mmHg
Molecular FormulaC27H30O16Melting Point220-250ºC
MSDS/Flash Point330.2ºC

Names

Name5-hydroxy-2-[4-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
SynonymMore Synonyms

Luteolin-3',7-di-O-glucoside BiologicalActivity

DescriptionLuteolin-3′,7-diglucoside is a glycoside isolate from R. luteolin. Luteolin-3′,7-diglucoside significantly inhibits cataracts induced in ovine lenses. Luteolin-3′,7-diglucoside inhibits the activity of Ureaplasma urealyticumATCC and clinical strains[1][2][3].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Others >>Others
Target

ATCC and clinical strains of Ureaplasma urealyticum[3]

In VitroLuteolin-3′,7-diglucoside (10 µM;24 h) 显著抑制在 45 % 低渗肝素缓冲溶液 (HBS) 中孵育 24 h 诱发的绵羊晶状体白内障[2]。 Luteolin-3′,7-diglucoside 抑制解脲支原体 ATCC 菌株的活性 (MIC=7.8-15.6 µM) 和解脲支原体临床菌株的活性 (MIC=0.48-1.95 µM)[3]。
References

[1]. Cristea D, et al. Identification and quantitative HPLC analysis of the main flavonoids present in weld (Reseda luteola L.)[J]. Dyes and Pigments, 2003, 57(3): 267-272.

[2]. Vit P, et al. Putative anticataract properties of honey studied by the action of flavonoids on a lens culture model[J]. Journal of Health Science, 2008, 54(2): 196-202.

[3]. Bisignano C, et al. In Vitro Efficacy of Crataegus oxycantha L.(Hawthorn) and Its Major Components against ATCC and Clinical Strains of Ureaplasma urealyticum[J]. Advances in Microbiology, 2016, 6(12): 909-916.

Chemical & Physical Properties

Density1.742 g/cm3
Boiling Point998ºC at 760 mmHg
Melting Point220-250ºC
Molecular FormulaC27H30O16
Molecular Weight610.51700
Flash Point330.2ºC
Exact Mass610.15300
PSA269.43000
Index of Refraction1.727
InChIKeyBISZYPSIZGKOFA-IPOZFMEPSA-N
SMILESO=c1cc(-c2ccc(O)c(OC3OC(CO)C(O)C(O)C3O)c2)oc2cc(OC3OC(CO)C(O)C(O)C3O)cc(O)c12

Synonyms

Luteolin-3',7-di-O-glucoside
EINECS 257-724-7
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