CAS 109376-05-8|Boc-Gln-Arg-Arg-AMC

Introduction:Basic information about CAS 109376-05-8|Boc-Gln-Arg-Arg-AMC, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBoc-Gln-Arg-Arg-AMC
CAS Number109376-05-8Molecular Weight715.80
Density/Boiling Point/
Molecular FormulaC32H49N11O8Melting Point/
MSDS/Flash Point/

Names

Nameboc-gln-arg-arg-amc acetate salt
SynonymMore Synonyms

Boc-Gln-Arg-Arg-AMC BiologicalActivity

DescriptionBoc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Tervonen TA, et, al. Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. Oncogene. 2016 Apr 7;35(14):1832-46.  

Chemical & Physical Properties

Molecular FormulaC32H49N11O8
Molecular Weight715.80
Exact Mass715.37700
PSA322.73000
LogP4.02270
InChIKeyGWQJHZHFUZJSAA-FKBYEOEOSA-N
SMILESCc1cc(=O)oc2cc(NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(N)=O)NC(=O)OC(C)(C)C)ccc12

Synonyms

Boc-Gln-Arg-Arg-7-amido-4-methylcoumarin acetate salt
BOC-GLN-ARG-ARG-AMC ACOH
T-BUTYLOXYCARBONYL-L-GLUTAMINYL-L-ARGINYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
Boc-Gln-Arg-Arg-AMC
N-T-BOC-GLN-ARG-ARG 7-AMIDO-4-*METHYLCOUMARIN ACETAT
N-T-boc-gln-arg-arg 7-amido-4-*methylcoumarin ace
N-tert-BOC-Gln-Arg-Arg 7-amido-4-methylcoumarin acetate
BOC-GLN-ARG-ARG-MCA
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CAS 88937-61-5|Z-Arg-Arg-AMC hydrochloride salt
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