Introduction：Basic information about CAS 756526-03-1|Bis-PEG5-NHS ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bis-PEG5-NHS ester |
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| CAS Number | 756526-03-1 | Molecular Weight | 532.49500 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C22H32N2O13 | Melting Point | / |
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| MSDS | USA | Flash Point | / |
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Names
| Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
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| Synonym | More Synonyms |
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Bis-PEG5-NHS ester BiologicalActivity
| Description | Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1. |
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Chemical & Physical Properties
| Molecular Formula | C22H32N2O13 |
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| Molecular Weight | 532.49500 |
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| Exact Mass | 532.19000 |
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| PSA | 173.51000 |
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| InChIKey | FTYUGLBWKRXQBD-UHFFFAOYSA-N |
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| SMILES | O=C(CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O |
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Synonyms
| Bis-PEG5-NHS ester |
| AmbotzPEG1435 |
| BIS-SUCCINIMIDYL-4,7,10,13,16-PENTAOXANONADECANE-1,19-DIOATE |
| B3728 |
| Bis-dPEG5-NHS ester |
