Introduction：Basic information about CAS 23434-88-0|Tetrahydropiperin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tetrahydropiperin |
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| CAS Number | 23434-88-0 | Molecular Weight | 289.369 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 469.9±24.0 °C at 760 mmHg |
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| Molecular Formula | C17H23NO3 | Melting Point | 41ºC |
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| MSDS | / | Flash Point | 238.0±22.9 °C |
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Names
| Name | 5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpentan-1-one |
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| Synonym | More Synonyms |
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Tetrahydropiperin BiologicalActivity
| Description | Tetrahydropiperine, a cyclohexyl analogue of piperine, is the first natural aryl pentanamide from Piper longum[1]. Tetrahydropiperine (compound 14) inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH; IC50=23 µM)[2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>Cytochrome P450 |
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| Target | CYP1A1:23 μM (IC50) |
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| References | [1]. Madhusudhan P, et al. Tetrahydropiperine, the first natural aryl pentanamide from Piper longum. Biochem Syst Ecol. 2001 May;29(5):537-538. [2]. Koul S, et al. Structure-activity relationship of piperine and its synthetic analogues for their inhibitory potentials of rat hepatic microsomal constitutive and inducible cytochromeP450 activities. Bioorg Med Chem. 2000 Jan;8(1):251-68. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 469.9±24.0 °C at 760 mmHg |
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| Melting Point | 41ºC |
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| Molecular Formula | C17H23NO3 |
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| Molecular Weight | 289.369 |
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| Flash Point | 238.0±22.9 °C |
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| Exact Mass | 289.167786 |
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| PSA | 38.77000 |
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| LogP | 3.67 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.556 |
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| InChIKey | APZYKUZPJCQGPP-UHFFFAOYSA-N |
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| SMILES | O=C(CCCCc1ccc2c(c1)OCO2)N1CCCCC1 |
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| Storage condition | -20℃ |
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Synonyms
| 1-[5-(1,3-Benzodioxol-5-yl)pentanoyl]piperidine |
| Tetrahydropiperidine |
| 5-(1,3-Benzodioxol-5-yl)-1-(piperidin-1-yl)pentan-1-one |
| Tetrahydropiperin |
| 1-Pentanone, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)- |
| 5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-1-pentanone |
| Piperidine, 1-[5-(1,3-benzodioxol-5-yl)-1-oxopentyl]- |
| Cosmoperine |
| Tetrahydropiperine |
