Introduction：Basic information about CAS 484-17-3|9-Phenanthrol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
9-Phenanthrol (9-Hydroxyphenanthrene) is a potent and selective human TRPM4 inhibitor, with an IC50 of 20 μM. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury[1][2].
Related Catalog
Signaling Pathways >>Membrane Transporter/Ion Channel >>TRP ChannelResearch Areas >>Cardiovascular Disease
References
[1]. Wang J, et, al. 9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury. PLoS One. 2013 Jul 25;8(7):e70587.
Chemical & Physical Properties
Density
1.2±0.1 g/cm3
Boiling Point
404.5±14.0 °C at 760 mmHg
Melting Point
139-143ºC
Molecular Formula
C14H10O
Molecular Weight
194.23
Flash Point
197.7±12.0 °C
Exact Mass
194.073166
PSA
20.23000
LogP
3.94
Vapour Pressure
0.0±1.0 mmHg at 25°C
Index of Refraction
1.754
InChIKey
DZKIUEHLEXLYKM-UHFFFAOYSA-N
SMILES
Oc1cc2ccccc2c2ccccc12
Storage condition
Refrigerator
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
SF8288000
CHEMICAL NAME :
9-Phenanthrol
CAS REGISTRY NUMBER :
484-17-3
BEILSTEIN REFERENCE NO. :
2047057
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H10-O
MOLECULAR WEIGHT :
194.24
WISWESSER LINE NOTATION :
L B666J HQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
5 mg/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 20,1297,1971
Safety Information
Personal Protective Equipment
dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes
Xi: Irritant;
Risk Phrases
R36/37/38
Safety Phrases
S26-S37/39
RIDADR
NONH for all modes of transport
WGK Germany
3
RTECS
SF8288000
HS Code
2906299090
Customs
HS Code
2906299090
Summary
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
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