CAS 673-49-4|N-ω-Acetylhistamine

Introduction:Basic information about CAS 673-49-4|N-ω-Acetylhistamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN-ω-Acetylhistamine
CAS Number673-49-4Molecular Weight153.18200
Density1.153g/cm3Boiling Point501.7ºC at 760 mmHg
Molecular FormulaC7H11N3OMelting Point147-149ºC(lit.)
MSDSChineseUSAFlash Point257.2ºC

Names

NameN-acetylhistamine
SynonymMore Synonyms

N-ω-Acetylhistamine BiologicalActivity

DescriptionN-acetylhistamine is a histamine metabolite. N-acetylhistamine can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
Related CatalogSignaling Pathways >>GPCR/G Protein >>Histamine ReceptorSignaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Inflammation/Immunology
In VitroN-acetylhistamine is an important indice for anaphylactoid reactions[1].
References

[1]. Xu Y, et al. Metabolomics analysis of anaphylactoid reaction reveals its mechanism in a rat model. Asian Pac J Allergy Immunol. 2017 Dec;35(4):224-232.

Chemical & Physical Properties

Density1.153g/cm3
Boiling Point501.7ºC at 760 mmHg
Melting Point147-149ºC(lit.)
Molecular FormulaC7H11N3O
Molecular Weight153.18200
Flash Point257.2ºC
Exact Mass153.09000
PSA57.78000
LogP0.47920
Index of Refraction1.533
InChIKeyXJWPISBUKWZALE-UHFFFAOYSA-N
SMILESCC(=O)NCCc1cnc[nH]1
Storage condition2-8℃

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety PhrasesS24/25
RIDADRNONH for all modes of transport
HS Code2933290090

Customs

HS Code2933290090
Summary2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles6

More Articles
[Oscillographic polarography of the alkaloid dolicotheline and several related imidazole derivatives].

Farmakol. Toksikol. 44(2) , 220-4, (1981)

Oscillographic polarography in an alkaline medium has shown that the alkaloid N-isovalerylhistamine appears as an expressive wave of the adsorption character in the cathode portion of the curve. This ...

Monooxygenation of N-acetylhistamine mediated by L-ascorbate.

Biochim. Biophys. Acta 991(2) , 377-9, (1989)

In the presence of molecular oxygen and a catalytic amount of copper(II) ion, ascorbate almost completely degraded histamine (approx. 72%). The reaction was shown to occur at the imidazole group but n...

Effects of intracerebroventricular administration of N-acetylhistamine on body temperature in mice.

Methods Find. Exp. Clin. Pharmacol. 16(8) , 575-81, (1994)

The purpose of this study was to examine the effects of intracerebroventricular (i.c.v.) administration of N-acetylhistamine on rectal temperature, histamine level, histidine decarboxylase (HDC) activ...

Synonyms

EINECS 211-610-3
Nomega-Acetylhistamine
N'-Acetylhistamine
N-[2-(1H-imidazol-5-yl)ethyl]acetamide
N-[2-(1H-Imidazol-4-yl)ethyl]acetamide
MFCD00005209
4-(2-acetamidoethyl)imidazole
Nw-acetyl-histamine
Acetylhistamine
N-ω-Acetylhistamine
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