CAS 4682-48-8|Lactosylceramides (bovine buttermilk)

Introduction：Basic information about CAS 4682-48-8|Lactosylceramides (bovine buttermilk), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Lactosylceramides (bovine buttermilk) BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Articles26
7. Synonyms

Common Name	Lactosylceramides (bovine buttermilk)
CAS Number	4682-48-8	Molecular Weight	960.36800
Density	1.14g/cm3	Boiling Point	1001.4ºC at 760 mmHg
Molecular Formula	C₅₃H₁₀₁NO₁₃	Melting Point	/
MSDS	USA	Flash Point	559.4ºC

Names

Name	CDH Ceramide β-lactoside Ceramide dihexoside Ceramide-β-D-lactoside
Synonym	More Synonyms

Lactosylceramides (bovine buttermilk) BiologicalActivity

Description	Lactosylceramide (LacCer) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others

Chemical & Physical Properties

Density	1.14g/cm3
Boiling Point	1001.4ºC at 760 mmHg
Molecular Formula	C₅₃H₁₀₁NO₁₃
Molecular Weight	960.36800
Flash Point	559.4ºC
Exact Mass	959.72700
PSA	227.86000
LogP	8.53810
Index of Refraction	1.538
Storage condition	-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FK1000000

CHEMICAL NAME :: Ceramide, 1-O-(4-O-beta-D-galactopyranosyl-beta-glucopyranosyl) -

CAS REGISTRY NUMBER :: 4682-48-8

LAST UPDATED :: 199212

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Human Fibroblast

DOSE/DURATION :: 100 umol/L

REFERENCE :: ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 199,169,1992

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
RTECS	FK1000000

Articles26

Streptococcus suis capsular polysaccharide inhibits phagocytosis through destabilization of lipid microdomains and prevents lactosylceramide-dependent recognition.

Infect. Immun. 80(2) , 506-17, (2012)

Streptococcus suis type 2 is a major swine pathogen and a zoonotic agent, causing meningitis in both swine and humans. S. suis infects the host through the respiratory route, reaches the bloodstream, ...

Accumulation of lactosylceramide and overexpression of a PSC833-resistant P-glycoprotein in multidrug-resistant human sarcoma cells.

Oncol. Rep. 25(4) , 1161-7, (2011)

The selection pressure for resistance to chemotherapy is accompanied by the enhanced expression of ABC proteins and increased cellular glycosphingolipid content. Thus, a possible connection between gl...

Different mechanisms are involved in apoptosis induced by melanoma gangliosides on human monocyte-derived dendritic cells.

Glycobiology 19(6) , 576-82, (2009)

Tumor escape is linked to multiple mechanisms, notably the liberation, by tumor cells, of soluble factors that inhibit the function of dendritic cells (DC). We have shown that melanoma gangliosides im...

Synonyms

CDH

MFCD00133445

Lactocerebrosides from bovine brain

Recommended......