CAS 938-73-8|2-Ethoxybenzamide

Introduction：Basic information about CAS 938-73-8|2-Ethoxybenzamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 2-Ethoxybenzamide BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Customs
7. Articles26
8. Synonyms

Common Name	2-Ethoxybenzamide
CAS Number	938-73-8	Molecular Weight	165.189
Density	1.1±0.1 g/cm3	Boiling Point	302.0±25.0 °C at 760 mmHg
Molecular Formula	C₉H₁₁NO₂	Melting Point	129-134 °C
MSDS	USA	Flash Point	153.7±19.5 °C

Names

Name	2-Ethoxybenzamide
Synonym	More Synonyms

2-Ethoxybenzamide BiologicalActivity

Description	2-Ethoxybenzamide is widely used as an antipyretic anodyne.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Others

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	302.0±25.0 °C at 760 mmHg
Melting Point	129-134 °C
Molecular Formula	C₉H₁₁NO₂
Molecular Weight	165.189
Flash Point	153.7±19.5 °C
Exact Mass	165.078979
PSA	52.32000
LogP	1.40
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.538
InChIKey	SBNKFTQSBPKMBZ-UHFFFAOYSA-N
SMILES	CCOc1ccccc1C(N)=O
Water Solubility	<0.1 g/100 mL at 16 ºC

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV4900000

CHEMICAL NAME :: Benzamide, o-ethoxy-

CAS REGISTRY NUMBER :: 938-73-8

BEILSTEIN REFERENCE NO. :: 2208582

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C9-H11-N-O2

MOLECULAR WEIGHT :: 165.21

WISWESSER LINE NOTATION :: ZVR BO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2630 mg/kg

TOXIC EFFECTS :: Behavioral - sleep Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Behavioral - sleep Cardiac - other changes Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 544 gm/kg/54W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: Morphological transformation

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Fibroblast

DOSE/DURATION :: 500 mg/L

REFERENCE :: ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886- Volume(issue)/page/year: (96),55,1978

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
RTECS	CU4381000
HS Code	29242995

Customs

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles26

Simultaneous determination of polar pharmaceuticals and personal care products in biological organs and tissues.

J. Chromatogr. A. 1355 , 193-205, (2014)

In the present study, a sensitive and accurate isotope dilution method was developed for the simultaneous determination of 17 polar pharmaceutical and personal care product (PPCP) residues (logKow=1.4...

Assessment of groundwater pollution in Tokyo using PPCPs as sewage markers.

Environ. Sci. Technol. 46(3) , 1455-64, (2012)

While the occurrence of pharmaceuticals and personal care products (PPCPs) in groundwater has typically been reported in bank filtration sites, irrigated fields, septic tanks, and sewage disposal prac...

Modifying effects of a mixture of acetaminophen, aspirin, dipyrone and ethenzamide on a multiorgan initiation model and its carcinogenicity in male F344 rats.

Cancer Lett. 135(1) , 83-90, (1999)

Six-week-old male F344 rats were given a mixture of 0.01% diethylnitrosamine, 0.05% N-butyl-N-(4-hydroxybutyl)nitrosamine and 0.02% N-methyl-N'-nitro-N-nitrosoguanidine in their drinking water for 1 w...

Synonyms

2-Ethoxyphenylformamide

2-ethoxy-benzoic acid amide

Etamide

Ethosalicyl

Aethylaethersalicylsaeure-amid

Benzamide,2-ethoxy

2-Aethoxy-benzamid

EINECS 213-346-4

4-10-00-00175 (Beilstein Handbook Reference)

Pirosolvina

Ethenzamide

2-Ethoxybenzenecarbonamide

MFCD00007977

Phenetolcarbamide

Salicylamide o-Ethyl Ether

Benzamide, 2-ethoxy-

Etenzamide [DCIT]

2-Aethoxy-benzoesaeure-amid

Ethenzamide (JP15)

2-Ethoxybenzamide

o-Ethoxybenzamide

Etenzamide

Ethbenzamide

2-Ethoxybenzolcarboxamid

O-Aethyl-salicylamid

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