CAS 38806-38-1|Nicotinamide 1,N6-Ethenoadenine Dinucleotide
| Common Name | Nicotinamide 1,N6-Ethenoadenine Dinucleotide | ||
|---|---|---|---|
| CAS Number | 38806-38-1 | Molecular Weight | 687.44700 |
| Density | / | Boiling Point | / |
| Molecular Formula | C23H27N7O14P2 | Melting Point | / |
| MSDS | USA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Nicotinamide 1,N6-Ethenoadenine Dinucleotide |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) , a fluorescent analogue of NAD, is able to serve as a substrate for the bacterial toxincatalyzed G-ADP ribosylation of signal-transducing G-proteins. Nicotinamide 1,N6-ethenoadenine dinucleotide can be used as a fluorescent substrate for the studies of the ADP ribosylation reaction[1]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| References | [1]. Hingorani VN, et al. Fluorescent labeling of signal-transducing G-proteins. Pertussis toxin-catalyzed etheno-ADP ribosylation of transducin. J Biol Chem. 1988 Dec 25;263(36):19804-8. |
Chemical & Physical Properties
| Molecular Formula | C23H27N7O14P2 |
|---|---|
| Molecular Weight | 687.44700 |
| Exact Mass | 687.10900 |
| PSA | 319.10000 |
| InChIKey | JCDBQDNBEQHDHK-BSLNIGMPSA-N |
| SMILES | NC(=O)c1ccc[n+](C2OC(COP(=O)([O-])OP(=O)(O)OCC3OC(n4cnc5c4ncn4ccnc54)C(O)C3O)C(O)C2O)c1 |
| Storage condition | 20°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
Articles24
More Articles| Hormonal control of ADP-ribosyl cyclase activity in pancreatic acinar cells from rats. J. Biol. Chem. 278(36) , 33629-36, (2003) Cyclic ADP-ribose, a metabolite of NAD+ evokes Ca2+ release from intracellular stores in different cells. We have determined the activity of cADPr-producing enzymes (ADP-ribosyl cyclases) in different... | |
| NAD+ analogs substituted in the purine base as substrates for poly(ADP-ribosyl) transferase. FEBS Lett. 397 , 17-21, (1996) Poly(ADP-ribosyl) transferase (pADPRT) catalyzes the transfer of the ADP-ribose moiety from NAD+ onto proteins as well as onto protein-bound ADP-ribose. As a result, protein-bound polymers of ADP-ribo... | |
| Assay for ADP-ribosyl cyclase by reverse-phase high-performance liquid chromatography. Anal. Biochem. 299(2) , 218-26, (2001) Cyclic ADP-ribose (cADPR), a natural metabolite of beta-NAD(+), is a second messenger for Ca(2+) signaling in T cells. As a tool for purification and identification of ADP-ribosyl cyclase(s) in T cell... |
Synonyms
| 1,N6-ETHENO NAD |
| Nicotinamide 1,N6-ethenoadenine dinucleotide |
| Nicotinamide1,N6-EthenoadenineDinucleotide |
