CAS 2304-81-6|C18 CERAMIDE

Introduction:Basic information about CAS 2304-81-6|C18 CERAMIDE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameC18 CERAMIDE
CAS Number2304-81-6Molecular Weight565.95400
Density0.915g/cm3Boiling Point694.5ºC at 760 mmHg
Molecular FormulaC36H71NO3Melting Point99 - 101ºC
MSDS/Flash Point373.8ºC

Names

Namec18 ceramide
SynonymMore Synonyms

C18 CERAMIDE BiologicalActivity

DescriptionC18-Ceramide can promote exocytosis of glutamate from damaged neurons. C18-Ceramide promotes cell death in glioma cells. Ceramides is involved in diverse cellular functions, such as differentiation, cell cycle progression, cell-cell adhesion, senescence, and apoptosis[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References

[1]. Tang N, et al. Differential effects of ceramide species on exocytosis in rat PC12 cells. Exp Brain Res. 2007 Nov;183(2):241-7.  

[2]. Wang Z, et al. Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma. Oncotarget. 2017 Oct 23;8(61):104022-104036.  

Chemical & Physical Properties

Density0.915g/cm3
Boiling Point694.5ºC at 760 mmHg
Melting Point99 - 101ºC
Molecular FormulaC36H71NO3
Molecular Weight565.95400
Flash Point373.8ºC
Exact Mass565.54300
PSA69.56000
LogP10.73410
Vapour Pressure2.59E-22mmHg at 25°C
Index of Refraction1.479
InChIKeyVODZWWMEJITOND-NXCSZAMKSA-N
SMILESCCCCCCCCCCCCCC=CC(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC
Storage condition−20°C
StabilityStable, but may be heat sensitive - store below 4 C. Incompatible with strong oxidizing agents.

Safety Information

Safety PhrasesS24/25
HS Code29225000

Synonyms

STEAROYL CERAMIDE
ceramide c18
N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)stearamide
N-Stearoyl-D-erythro-sphingosine
N-stearoylsphingosine
Cer(d18:1/18:0)
N-STEAROYLSPHINGANINE
C18 DIHYDROCERAMIDE
N-(octadecanoyl)-sphing-4-enine
N-18:0 SPHINGANINE
C18-D-ERYTHRO-CERAMIDE
N-stearoyl-D-erythro-sphingosine
N-Stearoyl-D-sphingosine
18:0 CERAMIDE
N-((2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl)stearamide
(2S,3R,4E)-2-(N-stearoylamino)-4-octadecene-1,3-diol
N-STEAROYL CERAMIDE
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