CAS 886-38-4|DPC
| Common Name | DPC | ||
|---|---|---|---|
| CAS Number | 886-38-4 | Molecular Weight | 206.239 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 407.2±45.0 °C at 760 mmHg |
| Molecular Formula | C15H10O | Melting Point | 118-122 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 182.7±23.7 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | diphenylcyclopropenone |
|---|---|
| Synonym | More Synonyms |
DPC BiologicalActivity
| Description | Diphenylcyclopropenone (Diphencyprone) is a topical immunomodulatory agent that can be used for alopecia areata research[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Yugang Gong, et al. Diphenylcyclopropenone plays an effective therapeutic role by up-regulating the TSLP/OX40L/IL-13 pathway in severe alopecia areata. Exp Dermatol. 2021 Feb;30(2):278-283. [2]. Zekayi Kutlubay, et al. Assessment of treatment efficacy of diphenylcyclopropenone (DPCP) for alopecia areata. Turk J Med Sci. 2020 Dec 17;50(8):1817-1824. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 407.2±45.0 °C at 760 mmHg |
| Melting Point | 118-122 °C(lit.) |
| Molecular Formula | C15H10O |
| Molecular Weight | 206.239 |
| Flash Point | 182.7±23.7 °C |
| Exact Mass | 206.073166 |
| PSA | 17.07000 |
| LogP | 3.78 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.669 |
| InChIKey | HCIBTBXNLVOFER-UHFFFAOYSA-N |
| SMILES | O=c1c(-c2ccccc2)c1-c1ccccc1 |
| Storage condition | Refrigerator (+4°C) |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H317 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R43 |
| Safety Phrases | S36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles72
More Articles| Differential signaling by regulatory subunits of phosphoinositide-3-kinase influences cell survival in INS-1E insulinoma cells. Exp. Clin. Endocrinol. Diabetes 123(2) , 118-25, (2015) Class 1A phosphoinositide 3-kinase (PI3K) is essential for beta-cell growth and survival. Although PI3K has been studied extensively in diabetes the effect of alternatively spliced isoforms of the cat... | |
| Spider wrapping silk fibre architecture arising from its modular soluble protein precursor. Sci. Rep. 5 , 11502, (2015) Spiders store spidroins in their silk glands as high concentration aqueous solutions, spinning these dopes into fibres with outstanding mechanical properties. Aciniform (or wrapping) silk is the tough... | |
| Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions. J. Cell Biol. 206(6) , 779-97, (2014) Mechanisms by which microtubule plus ends interact with regions of cell-cell contact during tissue development and morphogenesis are not fully understood. We characterize a previously unreported inter... |
Synonyms
| 2,3-Diphenyl-2-cyclopropen-1-one |
| 2,3-diphenylcycloprop-2-en-1-one |
| 1,2-Diphenylcyclopropen-3-one |
| 2,3-Diphenylcycloprop-2-en-1-on |
| DPC |
| DPC (VAN) |
| 2-Cyclopropen-1-one, 2,3-diphenyl- |
| EINECS 212-948-4 |
| MFCD00001311 |
| DIPHENYLCYCLOPROPENONE |
| 1,2-Diphenylcyclopropenone |
