CAS 2387-23-7|1,3-Dicyclohexylurea
| Common Name | 1,3-Dicyclohexylurea | ||
|---|---|---|---|
| CAS Number | 2387-23-7 | Molecular Weight | 224.34 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 364.3±25.0 °C at 760 mmHg |
| Molecular Formula | C13H24N2O | Melting Point | 232-233 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 174.1±23.2 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 1,3-dicyclohexylurea |
|---|---|
| Synonym | More Synonyms |
1,3-Dicyclohexylurea BiologicalActivity
| Description | 1,3-Dicyclohexylurea (DCU) is an orally active and potent sEH (soluble epoxide hydrolase) inhibitor. Oral Delivery of 1,3-Dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive Rats[1]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular Disease |
| In Vivo | 1,3-Dicyclohexylurea (Sprague Dawley rats, 30 mg/kg, Orally, once) shows antihypertensive efficacy when milled to reduce particle size, thus improving dissolution and oral bioavailability[1]. |
| References | [1]. Ghosh S, et al. Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. Basic Clin Pharmacol Toxicol. 2008 May;102(5):453-8. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 364.3±25.0 °C at 760 mmHg |
| Melting Point | 232-233 °C(lit.) |
| Molecular Formula | C13H24N2O |
| Molecular Weight | 224.34 |
| Flash Point | 174.1±23.2 °C |
| Exact Mass | 224.188858 |
| PSA | 41.13000 |
| LogP | 3.85 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.586 |
| InChIKey | ADFXKUOMJKEIND-UHFFFAOYSA-N |
| SMILES | O=C(NC1CCCCC1)NC1CCCCC1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful;N: Dangerous for the environment; |
| Risk Phrases | 22-51/53 |
| Safety Phrases | S61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| HS Code | 2924299090 |
Customs
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| F0902-7614 |
| MFCD00003829 |
| Methanol, 1-(cyclohexylamino)-1-(cyclohexylimino)-, (E)- |
| EINECS 219-213-7 |
| N,N'-Dicyclohexylurea |
| 1,3-Dicyclohexylurea |
| N,N-Dicyclohexylurea |
| Urea, N,N'-dicyclohexyl- |
| Urea,3-dicyclohexyl |
| dicyclohexyl urea |
| N,N‘-Dicyclohexylurea |
| 1,3-dicyclohexyl-urea |
| N,N'-Dicyclohexylcarbamimidic acid |
| DCW |
| N,N′-Dicyclohexylurea |
| Urea,N'-dicyclohexyl |
| 1,3-dicyclohexylcarbodiimide |
| Urea,N,N'-dicyclohexyl |
