CAS 120595-80-4|acetaminophen glucuronide sodium salt
| Common Name | acetaminophen glucuronide sodium salt | ||
|---|---|---|---|
| CAS Number | 120595-80-4 | Molecular Weight | 349.27 |
| Density | / | Boiling Point | / |
| Molecular Formula | C14H16NNaO8 | Melting Point | 232-233ºC (dec) |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | p-Acetamidophenyl β-D-glucuronide sodium salt |
|---|---|
| Synonym | More Synonyms |
acetaminophen glucuronide sodium salt BiologicalActivity
| Description | Acetaminophen glucuronide is a safe and effectiveantipyretic analgesic. Acetaminophen glucuronide is potentially toxic to liverand kidney [1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>Others |
| References | [1]. MazaleuskayaLL, et al. PharmGKB summary: pathways of acetaminophen metabolism at thetherapeutic versus toxic doses. Pharmacogenet Genomics. 2015 Aug;25(8):416-26. |
Chemical & Physical Properties
| Melting Point | 232-233ºC (dec) |
|---|---|
| Molecular Formula | C14H16NNaO8 |
| Molecular Weight | 349.27 |
| Exact Mass | 349.07700 |
| PSA | 148.38000 |
| InChIKey | OINXIJJEOMGKPB-VWOGDOGESA-M |
| SMILES | CC(=O)Nc1ccc(OC2OC(C(=O)[O-])C(O)C(O)C2O)cc1.[Na+] |
| Storage condition | −20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi: Irritant; |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles8
More Articles| Transporter-mediated uptake of UDP-glucuronic acid by human liver microsomes: assay conditions, kinetics, and inhibition. Drug Metab. Dispos. 43(1) , 147-53, (2014) This study characterized the kinetics, variability, and factors that affect UDP-glucuronic acid (UDP-GlcUA) uptake by human liver microsomes (HLM). Biphasic kinetics were observed for UDP-GlcUA uptake... | |
| Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater. J. Pharm. Biomed. Anal. 106 , 61-70, (2015) An analytical methodology for the simultaneous determination of seven pharmaceuticals and two metabolites belonging to the non-steroidal anti-inflammatory drugs (NSAIDs) and analgesics therapeutic gro... | |
| The effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite: paracetamol glucuronide. Eur. J. Drug Metab. Pharmacokinet. 40 , 163-70, (2015) The study aimed to examine the effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite, paracetamol glucuronide. Both drugs share metabolic pathways in the liver... |
Synonyms
| MFCD00153898 |
| ACETAMINOPHEN GLUCURONIDE SODIUM SALT |
| Acetaminophen glucuronide,Paracetamol glucuronide |
| Acetaminophen glucuronide Paracetamol glucuronide |
