CAS 1210-33-9|5-chlorodibenzosuberane

CHEMICAL IDENTIFICATION

RTECS NUMBER :

HO8302000

CHEMICAL NAME :

5H-Dibenzo(a,d)cycloheptene, 10,11-dihydro-5-chloro-

CAS REGISTRY NUMBER :

1210-33-9

BEILSTEIN REFERENCE NO. :

0612280

LAST UPDATED :

199612

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C15-H13-Cl

MOLECULAR WEIGHT :

228.73

WISWESSER LINE NOTATION :

L C676&T&J BG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

180 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02165

J. Med. Chem. 35 , 2481, (1992)

A series of 70 triazine derivatives have been synthesized and tested for their capacity to modulate multidrug resistance (MDR) in DC-3F/AD and KB-A1 tumor cells in vitro, in comparison with verapamil ...