CAS 554-35-8|LINAMARIN
| Common Name | LINAMARIN | ||
|---|---|---|---|
| CAS Number | 554-35-8 | Molecular Weight | 247.24500 |
| Density | 1.41g/cm3 | Boiling Point | 473.3ºC at 760mmHg |
| Molecular Formula | C10H17NO6 | Melting Point | 142-143ºC |
| MSDS | ChineseUSA | Flash Point | 240ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | linamarin |
|---|---|
| Synonym | More Synonyms |
LINAMARIN BiologicalActivity
| Description | Linamarin, a natural compound, possesses anticancer activity[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| References | [1]. Christopher Avwoghokoghene Idibie, et al. Cytotoxicity of purified cassava linamarin to a selected cancer cell lines. Bioprocess Biosyst Eng. 2007 Jul;30(4):261-9. |
Chemical & Physical Properties
| Density | 1.41g/cm3 |
|---|---|
| Boiling Point | 473.3ºC at 760mmHg |
| Melting Point | 142-143ºC |
| Molecular Formula | C10H17NO6 |
| Molecular Weight | 247.24500 |
| Flash Point | 240ºC |
| Exact Mass | 247.10600 |
| PSA | 123.17000 |
| Index of Refraction | 1.549 |
| InChIKey | QLTCHMYAEJEXBT-ZEBDFXRSSA-N |
| SMILES | CC(C)(C#N)OC1OC(CO)C(O)C(O)C1O |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 42,539,1977 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 120 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,241,1985
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H332-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | 20/22-36/37/38 |
| RIDADR | NONH for all modes of transport |
| RTECS | TZ4850000 |
Articles32
More Articles| Synthesis and Characterization of Hapten-Protein Conjugates for Antibody Production against Cyanogenic Glycosides. J. Food Prot. 78 , 1408-13, (2015) Consumption of cyanogenic plants can cause serious health problems for humans. The ability to detect and quantify cyanogenic glycosides, capable of generating cyanide, could contribute to prevention o... | |
| A recycling pathway for cyanogenic glycosides evidenced by the comparative metabolic profiling in three cyanogenic plant species. Biochem. J. 469 , 375-89, (2015) Cyanogenic glycosides are phytoanticipins involved in plant defence against herbivores by virtue of their ability to release toxic hydrogen cyanide (HCN) upon tissue disruption. In addition, endogenou... | |
| Overexpression of hydroxynitrile lyase in cassava roots elevates protein and free amino acids while reducing residual cyanogen levels. PLoS ONE 6(7) , e21996, (2011) Cassava is the major source of calories for more than 250 million Sub-Saharan Africans, however, it has the lowest protein-to-energy ratio of any major staple food crop in the world. A cassava-based d... |
Synonyms
| Phaseolunatin |
| 2-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropanenitrile |
| LINAMARIN |
