CAS 554-35-8|LINAMARIN

Introduction:Basic information about CAS 554-35-8|LINAMARIN, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameLINAMARIN
CAS Number554-35-8Molecular Weight247.24500
Density1.41g/cm3Boiling Point473.3ºC at 760mmHg
Molecular FormulaC10H17NO6Melting Point142-143ºC
MSDSChineseUSAFlash Point240ºC
Symbol
GHS07
Signal WordWarning

Names

Namelinamarin
SynonymMore Synonyms

LINAMARIN BiologicalActivity

DescriptionLinamarin, a natural compound, possesses anticancer activity[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
References

[1]. Christopher Avwoghokoghene Idibie, et al. Cytotoxicity of purified cassava linamarin to a selected cancer cell lines. Bioprocess Biosyst Eng. 2007 Jul;30(4):261-9.

Chemical & Physical Properties

Density1.41g/cm3
Boiling Point473.3ºC at 760mmHg
Melting Point142-143ºC
Molecular FormulaC10H17NO6
Molecular Weight247.24500
Flash Point240ºC
Exact Mass247.10600
PSA123.17000
Index of Refraction1.549
InChIKeyQLTCHMYAEJEXBT-ZEBDFXRSSA-N
SMILESCC(C)(C#N)OC1OC(CO)C(O)C(O)C1O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ4850000
CHEMICAL NAME :
Propanenitrile, 2-(beta-D-glucopyranosyloxy)-2-methyl-
CAS REGISTRY NUMBER :
554-35-8
BEILSTEIN REFERENCE NO. :
0019237
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H17-N-O6
MOLECULAR WEIGHT :
247.28
WISWESSER LINE NOTATION :
T6OTJ BQ CQ DQ EQ FOX1&1&1CN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Gastrointestinal - hypermotility, diarrhea
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 42,539,1977 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
120 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,241,1985

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH302-H315-H319-H332-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn
Risk Phrases20/22-36/37/38
RIDADRNONH for all modes of transport
RTECSTZ4850000

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Synonyms

Phaseolunatin
2-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropanenitrile
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