Introduction:Basic information about CAS 3031-94-5|Aica ribonucleotide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.
Br. J. Cancer 111(8) , 1562-71, (2014)
The increasing usage of statins (the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) has revealed a number of unexpected beneficial effects, including a reduction in cancer risk.We investi...
Site-directed mutagenesis of catalytic residues in N(5)-carboxyaminoimidazole ribonucleotide synthetase.
Biochemistry 52(37) , 6559-67, (2013)
N(5)-CAIR synthetase, an essential enzyme in microorganisms, converts 5-aminoimidazole ribonucleotide (AIR) and bicarbonate to N(5)-CAIR with the aid of ATP. Previous X-ray crystallographic analyses o...
Genistein suppresses LPS-induced inflammatory response through inhibiting NF-κB following AMP kinase activation in RAW 264.7 macrophages.
PLoS ONE 7(12) , e53101, (2012)
Genistein, the major isoflavone in soybean, was recently reported to exert beneficial effects in metabolic disorders and inflammatory diseases. In the present study, we investigated the effects and me...