CAS 23783-42-8|Tetraethylene glycol monomethyl ether
Introduction：Basic information about CAS 23783-42-8|Tetraethylene glycol monomethyl ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Tetraethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target
PEGs
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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