CAS 480-16-0|Morin

Introduction：Basic information about CAS 480-16-0|Morin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Morin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Articles39
7. Synonyms

Common Name	Morin
CAS Number	480-16-0	Molecular Weight	302.236
Density	1.8±0.1 g/cm3	Boiling Point	645.5±55.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₀O₇	Melting Point	299-300 °C (dec.)(lit.)
MSDS	ChineseUSA	Flash Point	249.3±25.0 °C
Symbol	GHS06	Signal Word	Danger

Names

Name	morin
Synonym	More Synonyms

Morin BiologicalActivity

Description	Morin, a plant-derived flavonoid, possesses low antioxidant activity. Morin is a fluorescing chelating agent used in aluminum speciation[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Duthie G, et al. Antioxidant capacity of flavonoids in hepatic microsomes is not reflected by antioxidant effects in vivo. Oxid Med Cell Longev. 2012;2012:165127. [2]. Lian HZ, et al. Morin applied in speciation of aluminium in natural waters and biological samples by reversed-phase high-performance liquid chromatography with fluorescence detection. Anal Bioanal Chem. 2003 Jun;376(4):542-8. Epub 2003 May 9.

Description

Morin, a plant-derived flavonoid, possesses low antioxidant activity. Morin is a fluorescing chelating agent used in aluminum speciation[1][2].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Duthie G, et al. Antioxidant capacity of flavonoids in hepatic microsomes is not reflected by antioxidant effects in vivo. Oxid Med Cell Longev. 2012;2012:165127.

[2]. Lian HZ, et al. Morin applied in speciation of aluminium in natural waters and biological samples by reversed-phase high-performance liquid chromatography with fluorescence detection. Anal Bioanal Chem. 2003 Jun;376(4):542-8. Epub 2003 May 9.

Chemical & Physical Properties

Density	1.8±0.1 g/cm3
Boiling Point	645.5±55.0 °C at 760 mmHg
Melting Point	299-300 °C (dec.)(lit.)
Molecular Formula	C₁₅H₁₀O₇
Molecular Weight	302.236
Flash Point	249.3±25.0 °C
Exact Mass	302.042664
PSA	131.36000
LogP	1.61
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.823
InChIKey	YXOLAZRVSSWPPT-UHFFFAOYSA-N
SMILES	O=c1c(O)c(-c2ccc(O)cc2O)oc2cc(O)cc(O)c12
Stability	Stable. Incompatible with strong oxidizing agents.
Water Solubility	methanol: 50 mg/mL

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LK8749000

CHEMICAL NAME :: Flavone, 2',3,4',5,7-pentahydroxy-

CAS REGISTRY NUMBER :: 480-16-0

BEILSTEIN REFERENCE NO. :: 0327474

LAST UPDATED :: 199801

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C15-H10-O7

MOLECULAR WEIGHT :: 302.25

WISWESSER LINE NOTATION :: T66 BO EVJ CR BQ DQ& DQ GQ IQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 555 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 10 umol/L

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 35,443,1997

Safety Information

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301
Precautionary Statements	P301 + P310
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
RTECS	LK8749000

Articles39

The toxicity of NaF on BmN cells and a comparative proteomics approach to identify protein expression changes in cells under NaF-stress: impact of NaF on BmN cells.

J. Hazard. Mater. 286 , 624-31, (2015)

Fluorides negatively affect the development of organisms and are a threat to human health and environmental safety. In this study, Bombyx mori N cell line (BmN) were used to explore effects of NaF on ...

In vitro effects of myricetin, morin, apigenin, (+)-taxifolin, (+)-catechin, (-)-epicatechin, naringenin and naringin on cytochrome b5 reduction by purified NADH-cytochrome b5 reductase.

Toxicology 308 , 34-40, (2013)

The microsomal NADH-dependent electron transport system consisting of cytochrome b5 reductase and cytochrome b5 participates in a number of physiologically important processes including lipid metaboli...

Enhanced oral bioavailability of morin administered in mixed micelle formulation with PluronicF127 and Tween80 in rats.

Biol. Pharm. Bull. 38(2) , 208-17, (2015)

To overcome the low oral bioavailability of morin, a mixed micelle formulation with pharmaceutical excipients that facilitate solubilization and modulate P-glycoprotein (P-gp) was developed and evalua...

Synonyms

Aluminum Ionophore I

Aurantica

Morin

Morin hydrate

EINECS 207-542-9

MFCD00006826

2',3,4',5,7-Pentahydroxyflavone

2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one

Bois d'Arc

4H-1-Benzopyran-4-one, 2- (2,4-dihydroxyphenyl)-3,5,7-trihydroxy-

4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-

Calico Yellow

Al-Morin

Osage Orange

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