CAS 2719-05-3|4,4'-diacetamidodiphenylmethane

Introduction:Basic information about CAS 2719-05-3|4,4'-diacetamidodiphenylmethane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name4,4'-diacetamidodiphenylmethane
CAS Number2719-05-3Molecular Weight282.337
Density1.2±0.1 g/cm3Boiling Point564.6±43.0 °C at 760 mmHg
Molecular FormulaC17H18N2O2Melting Point/
MSDSChineseUSAFlash Point217.8±28.3 °C
Symbol
GHS09
Signal WordWarning

Names

Name4,4'-diacetamidodiphenylmethane
SynonymMore Synonyms

4,4'-diacetamidodiphenylmethane BiologicalActivity

DescriptionFH1(BRDK4477) is a small molecule that can enhance the functions of cultured hepatocytes.IC50 value:Target: In vitro: FH1(BRD-K4477) enhances hepatocyte functions, and promotes the maturation of well-differentiated cultures of iHeps, which potentially alleviates a major obstacle to the use of iPS cells as a renewable source of functional human hepatocytes.
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Others
References

[1]. Shan J, et al. Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nat Chem Biol. 2013 Aug;9(8):514-20.

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point564.6±43.0 °C at 760 mmHg
Molecular FormulaC17H18N2O2
Molecular Weight282.337
Flash Point217.8±28.3 °C
Exact Mass282.136841
PSA58.20000
LogP1.93
Vapour Pressure0.0±1.5 mmHg at 25°C
Index of Refraction1.635
InChIKeyOEXMNSOPAKOPEF-UHFFFAOYSA-N
SMILESCC(=O)Nc1ccc(Cc2ccc(NC(C)=O)cc2)cc1
Storage condition-20℃

Safety Information

Symbol
GHS09
Signal WordWarning
Hazard StatementsH400
Precautionary StatementsP273
Risk PhrasesR22;R40
Safety PhrasesS22-S36/37
RIDADRUN 3077 9 / PGIII

Synonyms

N,N'-AcetylMDA
4.4'-Bis-acetamino-diphenylmethan
N,N'-diacetyl-4,4'-methylenedianiline
4,4'-diacetoamino-diphenylmethane
N,N'-(Methylenedi-4,1-phenylene)diacetamide
4',4''-METHYLENEBIS(ACETANILIDE)
N1-{4-[4-(acetylamino)benzyl]phenyl}acetamide
4,4'-Diacetyldiaminodiphenylmethan
Acetamide, N,N'-(methylenedi-4,1-phenylene)bis-
N-[4-[(4-Acetamidophenyl)Methyl]Phenyl]Acetamide
BRD-K4477
FH1
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