CAS 2711-58-2|5-Fluorotryptamine hydrochloride

Introduction：Basic information about CAS 2711-58-2|5-Fluorotryptamine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles5
7. Synonyms

Common Name	5-Fluorotryptamine hydrochloride
CAS Number	2711-58-2	Molecular Weight	214.667
Density	1.3±0.1 g/cm3	Boiling Point	346.0±27.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₂ClFN₂	Melting Point	277-283
MSDS	ChineseUSA	Flash Point	163.0±23.7 °C

Names

Name	2-(5-Fluoro-1H-indol-3-yl)ethanamine hydrochloride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	346.0±27.0 °C at 760 mmHg
Melting Point	277-283
Molecular Formula	C₁₀H₁₂ClFN₂
Molecular Weight	214.667
Flash Point	163.0±23.7 °C
Exact Mass	214.067307
PSA	41.81000
LogP	1.52
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.644
InChIKey	YZAWADGJXKCLTI-UHFFFAOYSA-N
SMILES	Cl.NCCc1c[nH]c2ccc(F)cc12
Storage condition	−20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL4055600

CHEMICAL NAME :: Indole, 3-(2-aminoethyl)-5-fluoro-, hydrochloride

CAS REGISTRY NUMBER :: 2711-58-2

LAST UPDATED :: 199206

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H11-F-N2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 529 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 16,200,1960

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NL4055600
HS Code	2942000000

Customs

HS Code	2942000000

Articles5

5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function.

Eur. J. Pharmacol. 580(3) , 291-7, (2008)

Antagonists, but not agonists, of the 5-HT3 receptor are useful therapeutic agents, and it is possible that partial agonists may also be potentially useful in the clinic. Here we show that 5-fluorotry...

Quantitative determination of melatonin in human plasma and cerebrospinal fluid with high-performance liquid chromatography and fluorescence detection.

Biomed. Chromatogr. 14(5) , 306-10, (2000)

A validated new and precise reversed-phase high-performance liquid chromatographic method for the determination of melatonin in human plasma and cerebrospinal fluid, with 5-fluorotryptamine as interna...

Thrombin: active-site topography.

Ann. N. Y. Acad. Sci. 485 , 80-95, (1986)

Synonyms

5-Fluorotryptaminehydrochloride

2-(5-Fluoro-1H-indol-3-yl)ethanamine

1H-Indole-3-ethanamine, 5-fluoro-, monohydrochloride (9CI)

1H-Indole-3-ethanamine, 5-fluoro-

1H-Indole-3-ethanamine, 5-fluoro-, hydrochloride (1:1)

5-Fluorotryptamine hydrochloride

2-(5-fluoro-1H-indol-3-yl)ethanamine,hydrochloride

EINECS 220-307-5

MFCD00051081

2-(5-Fluoro-1H-indol-3-yl)ethanamine hydrochloride (1:1)

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