CAS 544-31-0|Palmitoylethanolamide
| Common Name | Palmitoylethanolamide | ||
|---|---|---|---|
| CAS Number | 544-31-0 | Molecular Weight | 299.492 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 461.5±28.0 °C at 760 mmHg |
| Molecular Formula | C18H37NO2 | Melting Point | 99 °C |
| MSDS | ChineseUSA | Flash Point | 232.9±24.0 °C |
Names
| Name | palmitoyl ethanolamide |
|---|---|
| Synonym | More Synonyms |
Palmitoylethanolamide BiologicalActivity
| Description | AM 3112 is an active endogenous compound which can used for preventing virus infection of the respiratory tract. |
|---|---|
| Related Catalog | Natural Products >>OthersResearch Areas >>Infection |
| Target | Human Endogenous Metabolite |
| In Vitro | AM 3112 (Impulsin) itself does not stimulate interferon production in mice treated per os or intravenously. But repeated application of this drug per os induces a macrophage activation, reflected by enhanced interferon production in vitro. When the interferon stimulation is delayed until 4 to 10 days after the first dose of AM 3112, interferon response to ds-RNA is slightly increased. After this phase of enhanced activity a decreased production of interferon is observed. AM 3112 is not significantly effective in protecting mice from lethal dose of EMC virus. Application of this drug has an inhibitory effect on the toxicity of ds-RNA. A possible explanation of the mechanism by which AM 3112 decreased the toxicity of virus in the organism is discussed[1]. |
| References | [1]. Lackovic V, et al. Effect of impulsin treatment of interferon production and antiviral resistance of mice. Arch Immunol Ther Exp (Warsz). 1977;25(5):655-61. |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 461.5±28.0 °C at 760 mmHg |
| Melting Point | 99 °C |
| Molecular Formula | C18H37NO2 |
| Molecular Weight | 299.492 |
| Flash Point | 232.9±24.0 °C |
| Exact Mass | 299.282440 |
| PSA | 49.33000 |
| LogP | 5.82 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.463 |
| InChIKey | HXYVTAGFYLMHSO-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCC(=O)NCCO |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| HS Code | 2924199090 |
Customs
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Palmitoyl Ethanolamide |
| Palmitoylethanolamide |
| palmidrol |
| EINECS 208-867-9 |
| N-(2-Hydroxyethyl)hexadecanamide |
| MFCD00020562 |
| Hexadecanamide, N-(2-hydroxyethyl)- |
| AM 3112 |
