Introduction：Basic information about CAS 167144-79-8|R-96544 hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | R-96544 hydrochloride |
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| CAS Number | 167144-79-8 | Molecular Weight | 355.47 |
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| Density | / | Boiling Point | 484.5ºC at 760mmHg |
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| Molecular Formula | C22H29NO3 | Melting Point | / |
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| MSDS | / | Flash Point | 246.8ºC |
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Names
| Name | (2R,4R)-4-hydroxy-2-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methylpyrrolidine |
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R-96544 hydrochloride BiologicalActivity
| Description | R-96544 (free base) is a potent, selective and competitive 5-HT2 receptor antagonist. R-96544 (free base) inhibits platelet aggregation induced by serotonin, and inhibits 5-HT2A receptor-mediated contraction of guinea pig trachea[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>GPCR/G Protein >>5-HT ReceptorSignaling Pathways >>Neuronal Signaling >>5-HT Receptor |
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| References | [1]. Ogawa T,et al. Pharmacological profiles of R-96544, the active form of a novel 5-HT2A receptor antagonist R-102444. Eur J Pharmacol. 2002;457(2-3):107-114. doi:10.1016/s0014-2999(02)02654-7 |
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Chemical & Physical Properties
| Boiling Point | 484.5ºC at 760mmHg |
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| Molecular Formula | C22H29NO3 |
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| Molecular Weight | 355.47 |
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| Flash Point | 246.8ºC |
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| Exact Mass | 391.19100 |
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| PSA | 41.93000 |
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| LogP | 4.05420 |
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| Vapour Pressure | 3.35E-10mmHg at 25°C |
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| InChIKey | OUKRSTJUAQEATQ-UHFFFAOYSA-N |
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| SMILES | COc1cccc(CCc2ccccc2OCCC2CC(O)CN2C)c1.Cl |
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