Introduction：Basic information about CAS 14279-91-5|4-Chlorophenylguanidine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Chlorophenylguanidine hydrochloride |
|---|
| CAS Number | 14279-91-5 | Molecular Weight | 206.07 |
|---|
| Density | / | Boiling Point | 333.9ºC at 760mmHg |
|---|
| Molecular Formula | C7H9Cl2N3 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 155.7ºC |
|---|
Names
| Name | 2-(4-chlorophenyl)guanidine,hydrochloride |
|---|
| Synonym | More Synonyms |
|---|
4-Chlorophenylguanidine hydrochloride BiologicalActivity
| Description | 4-Chlorophenylguanidine hydrochloride is a potent ASIC3 positive allosteric modulator and reverses the effects of ASIC3 desensitization. 4-Chlorophenylguanidine hydrochloride influences ASIC3 activity through directly activating the channel and increasing proton sensitivity. 4-Chlorophenylguanidine hydrochloride offers a chemical backbone for the design of new ASIC3 ligands to study ASIC3 in vivo[1]. |
|---|
| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Sodium ChannelResearch Areas >>Neurological Disease |
|---|
| References | [1]. Amruta S Agharkar, et al. 4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator. J Pharmacol Sci. 2017 Mar;133(3):184-186. |
|---|
Chemical & Physical Properties
| Boiling Point | 333.9ºC at 760mmHg |
|---|
| Molecular Formula | C7H9Cl2N3 |
|---|
| Molecular Weight | 206.07 |
|---|
| Flash Point | 155.7ºC |
|---|
| Exact Mass | 205.01700 |
|---|
| PSA | 61.90000 |
|---|
| LogP | 3.32040 |
|---|
| Vapour Pressure | 0.000133mmHg at 25°C |
|---|
| InChIKey | RMFZXBDENVVLSL-UHFFFAOYSA-N |
|---|
| SMILES | Cl.NC(N)=Nc1ccc(Cl)cc1 |
|---|
Safety Information
| Hazard Codes | Xi |
|---|
| HS Code | 2925290090 |
|---|
Customs
| HS Code | 2925290090 |
|---|
| Summary | 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
|---|
Synonyms
| bw 65-100 |
| 4-chlorophenylguanidine hydrochloride |
| 4-chlorophenylguanidine |
