Introduction：Basic information about CAS 200432-86-6|UB 165 fumarate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | UB 165 fumarate |
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| CAS Number | 200432-86-6 | Molecular Weight | 350.79700 |
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| Density | / | Boiling Point | 597.4ºC at 760mmHg |
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| Molecular Formula | C17H19ClN2O4 | Melting Point | / |
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| MSDS | / | Flash Point | 315.1ºC |
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Names
| Name | UB 165 fumarate,2-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-2-enefumarate |
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| Synonym | More Synonyms |
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UB 165 fumarate BiologicalActivity
| Description | UB-165 is a nAChR agonist, being a full agonist of the α3β2 isoform and a partial agonist of the α4β2* isoform, with a Ki value of 0.27 nM for [3H]-nicotine binding in rat brain[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>nAChRSignaling Pathways >>Neuronal Signaling >>nAChRResearch Areas >>Neurological Disease |
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| In Vitro | UB-165 刺激 [3H]-多巴胺从纹状体突触释放，EC50 值为 88 nM[1]。 |
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| References | [1]. Sharples CG, et al. UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes. J Neurosci. 2000 Apr 15;20(8):2783-91. |
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Chemical & Physical Properties
| Boiling Point | 597.4ºC at 760mmHg |
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| Molecular Formula | C17H19ClN2O4 |
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| Molecular Weight | 350.79700 |
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| Flash Point | 315.1ºC |
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| Exact Mass | 350.10300 |
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| PSA | 99.52000 |
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| LogP | 3.07340 |
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Synonyms
| Compound 401 |
| UB 165 FUMARATE |
