Introduction：Basic information about CAS 149184-21-4|CGP 54626 hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | CGP 54626 hydrochloride |
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| CAS Number | 149184-21-4 | Molecular Weight | 444.76100 |
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| Density | / | Boiling Point | 632.4ºC at 760mmHg |
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| Molecular Formula | C18H29Cl3NO3P | Melting Point | / |
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| MSDS | / | Flash Point | 336.3ºC |
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Names
| Name | cyclohexylmethyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid,hydrochloride |
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CGP 54626 hydrochloride BiologicalActivity
| Description | CGP 54626 (hydrochloride) is a selective antagonist of GABAB receptor with an IC50 value of 4 nM. CGP 54626 (hydrochloride) can be used to investigate the role of GABAB receptors in neurological signaling[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
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| References | [1]. Kaupmann K, et al. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature. 1998 Dec 17;396(6712):683-7. |
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Chemical & Physical Properties
| Boiling Point | 632.4ºC at 760mmHg |
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| Molecular Formula | C18H29Cl3NO3P |
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| Molecular Weight | 444.76100 |
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| Flash Point | 336.3ºC |
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| Exact Mass | 443.09500 |
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| PSA | 79.37000 |
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| LogP | 6.04850 |
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| Vapour Pressure | 7.3E-17mmHg at 25°C |
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| InChIKey | ZQCFHOVIXCJPLE-LINSIKMZSA-N |
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| SMILES | CC(NCC(O)CP(=O)(O)CC1CCCCC1)c1ccc(Cl)c(Cl)c1.Cl |
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