CAS 127299-93-8|BRL 37344, sodium salt

Introduction：Basic information about CAS 127299-93-8|BRL 37344, sodium salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BRL 37344, sodium salt BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	BRL 37344, sodium salt
CAS Number	127299-93-8	Molecular Weight	385.81700
Density	/	Boiling Point	569.7ºC at 760mmHg
Molecular Formula	C₁₉H₂₁ClNNaO₄	Melting Point	/
MSDS	ChineseUSA	Flash Point	298.4ºC

Names

Name	BRL 37344 sodium salt hydrate
Synonym	More Synonyms

BRL 37344, sodium salt BiologicalActivity

Description	BRL 37344 sodium (BRL 37344A) is a specific β3-adrenergic receptor agonist. BRL 37344 sodium treatment significantly lowers the body weight of obese mice[1].
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Metabolic Disease
Target	β3-adrenergic receptor[1]
In Vivo	BRL37344 sodium (BRL 37344A) treatment significantly lowers the body weight of obese mice[1]. Animal Model: Five-week-old male Imprinting Control Region (ICR) mice[1] Dosage: 2.5 mg/kg Administration: Intraperitoneal injection; three times per week for two weeks Result: Lowered the body weight of obese mice.
References	[1]. Wu C, et al. Activating brown adipose tissue for weight loss and lowering of blood glucose levels: a microPET study using obese and diabetic model mice. PLoS One. 2014 Dec 2;9(12):e113742.

Chemical & Physical Properties

Boiling Point	569.7ºC at 760mmHg
Molecular Formula	C₁₉H₂₁ClNNaO₄
Molecular Weight	385.81700
Flash Point	298.4ºC
Exact Mass	385.10600
PSA	81.62000
LogP	2.11380
Vapour Pressure	8.09E-14mmHg at 25°C
InChIKey	SNJIJYKMYQRHRC-WJKBNZMCSA-M
SMILES	CC(Cc1ccc(OCC(=O)[O-])cc1)NCC(O)c1cccc(Cl)c1.[Na+]

Safety Information

Safety Phrases	S22-S24/25

Synonyms

sodium,2-[4-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetate

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