CAS 487-53-6|Hydroxyprocaine

Introduction：Basic information about CAS 487-53-6|Hydroxyprocaine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Synonyms

Common Name	Hydroxyprocaine
CAS Number	487-53-6	Molecular Weight	252.30900
Density	1.158g/cm3	Boiling Point	408.7ºC at 760mmHg
Molecular Formula	C₁₃H₂₀N₂O₃	Melting Point	/
MSDS	/	Flash Point	201ºC

Names

Name	2-(diethylamino)ethyl 4-amino-2-hydroxybenzoate
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.158g/cm3
Boiling Point	408.7ºC at 760mmHg
Molecular Formula	C₁₃H₂₀N₂O₃
Molecular Weight	252.30900
Flash Point	201ºC
Exact Mass	252.14700
PSA	75.79000
LogP	2.05420
Vapour Pressure	2.9E-07mmHg at 25°C
Index of Refraction	1.565
InChIKey	GHSCYMOJHVOGDJ-UHFFFAOYSA-N
SMILES	CCN(CC)CCOC(=O)c1ccc(N)cc1O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VO1575000

CHEMICAL NAME :: Salicylic acid, 4-amino-, 2-(diethylamino)ethyl ester

CAS REGISTRY NUMBER :: 487-53-6

BEILSTEIN REFERENCE NO. :: 2650192

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C13-H20-N2-O3

MOLECULAR WEIGHT :: 252.35

WISWESSER LINE NOTATION :: ZR CQ DVO2N2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 190 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 36 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 2,112,1952

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 47 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 31,97,1953

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 72 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 10,284,1951

Safety Information

HS Code	2922509090

Customs

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

4-Amino-2-hydroxy-benzoesaeure-(2-diaethylamino-aethylester)

Metahydroxyprocaine

Oxyprocain

Hydroxyprocaine

Oxycaine

Hydroxynovocain

2-Diethylaminoethyl p-aminosalicylate

4-Amino-salicylsaeure-(2-diethylamino-ethylester)

Oxyprocaine

m-Hydroxyprocaine

Oxiprocainum

4-Amino-2-hydroxy-benzoesaeure-(2-diethylamino-ethylester)

p-Amino-salicylsaeure-diaethylaminoaethyl-ester

Hydroxy-procain

4-amino-2-hydroxy-benzoic acid-(2-diethylamino-ethyl ester)

Diethylaminoethyl p-aminosalicylate

MFCD00047845

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