Introduction：Basic information about CAS 146-54-3|triflupromazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | triflupromazine |
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| CAS Number | 146-54-3 | Molecular Weight | 352.41700 |
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| Density | 1.238g/cm3 | Boiling Point | 427.6ºC at 760mmHg |
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| Molecular Formula | C18H19F3N2S | Melting Point | 25°C |
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| MSDS | / | Flash Point | 212.4ºC |
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Names
| Name | triflupromazine |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.238g/cm3 |
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| Boiling Point | 427.6ºC at 760mmHg |
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| Melting Point | 25°C |
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| Molecular Formula | C18H19F3N2S |
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| Molecular Weight | 352.41700 |
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| Flash Point | 212.4ºC |
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| Exact Mass | 352.12200 |
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| PSA | 31.78000 |
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| LogP | 5.32480 |
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| Index of Refraction | nD23 1.5780 |
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| InChIKey | XSCGXQMFQXDFCW-UHFFFAOYSA-N |
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| SMILES | CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- SO8850000
- CHEMICAL NAME :
- Phenothiazine, 10-(3-(dimethylamino)propyl)-2-(trifluoromethyl)-
- CAS REGISTRY NUMBER :
- 146-54-3
- LAST UPDATED :
- 199201
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C18-H19-F3-N2-S
- MOLECULAR WEIGHT :
- 352.45
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B3N1&1 EXFFF
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 185 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 94 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 245 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 34 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 25 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 17,87,1973
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Safety Information
Customs
| HS Code | 2934300000 |
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| Summary | 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| dimethyl-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-amine |
| Siquil |
| EINECS 205-673-6 |
| N,N-dimethyl-2-(trifluoromethyl)-10H-phenothiazine-10-propanamine |
| Adazine |
| Vesprin |
| Triflupromazina |
| Vetame |
| Psyquil |
| Triflupromazinum |
| Trifluopromazine |
| 2-trifluoromethyl-10-[3-(dimethylamino)propyl]phenothiazine |
| N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine |
| Fluopromazine |
