Introduction：Basic information about CAS 339-44-6|N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-[5-(2-methoxyethoxy)-2-pyrimidinyl]benzenesulphonamide |
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| CAS Number | 339-44-6 | Molecular Weight | 309.34100 |
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| Density | 1.354g/cm3 | Boiling Point | 515.1ºC at 760mmHg |
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| Molecular Formula | C13H15N3O4S | Melting Point | / |
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| MSDS | / | Flash Point | 265.4ºC |
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Names
| Name | N-[5-(2-methoxyethoxy)pyrimidin-2-yl]benzenesulfonamide |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Glymidine (Glidiazine) is a hypoglycaemic agent. Glymidine is a lipid soluble sulphapyrimidine derivative. Glymidine appears to stimulate insulin release from pancreas. Glymidine is a possible alternative to the sulphonylureas and biguanides for the research of diabetes mellitus[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| References | [1]. Glymidine. Br Med J. 1967;2(5555):817. |
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Chemical & Physical Properties
| Density | 1.354g/cm3 |
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| Boiling Point | 515.1ºC at 760mmHg |
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| Molecular Formula | C13H15N3O4S |
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| Molecular Weight | 309.34100 |
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| Flash Point | 265.4ºC |
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| Exact Mass | 309.07800 |
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| PSA | 98.79000 |
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| LogP | 2.45640 |
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| Index of Refraction | 1.588 |
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| InChIKey | QFWPJPIVLCBXFJ-UHFFFAOYSA-N |
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| SMILES | COCCOc1cnc(NS(=O)(=O)c2ccccc2)nc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DB2910000
- CHEMICAL NAME :
- Benzenesulfonamide, N-(5-(2-methoxyethoxy)-2-pyrimidinyl)-
- CAS REGISTRY NUMBER :
- 339-44-6
- BEILSTEIN REFERENCE NO. :
- 0552655
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C13-H15-N3-O4-S
- MOLECULAR WEIGHT :
- 309.37
- WISWESSER LINE NOTATION :
- T6N CNJ BMSWR& EO201
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3100 mg/kg
- TOXIC EFFECTS :
- Endocrine - hypoglycemia
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,377,1964
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Safety Information
Customs
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Synonyms
| Glycodiazin |
| Glycodiazin [German] |
| EINECS 206-426-5 |
| N-[5-(2-methoxy-ethoxy)-pyrimidin-2-yl]-benzenesulfonamide |
| GLYMIDINE |
| UNII-4C5I4BQZ8F |
| Glymidinum |
| Glycodiazine |
| Glidiazine |
