Introduction：Basic information about CAS 105659-32-3|5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE |
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| CAS Number | 105659-32-3 | Molecular Weight | 449.21 |
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| Density | 1.66g/cm3 | Boiling Point | / |
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| Molecular Formula | C15H17BrN2O9 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-Bromo-2',3',5'-tri-O-acetyluridine |
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| Synonym | More Synonyms |
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5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE BiologicalActivity
| Description | 5-Bromo-2',3',5'-tri-O-acetyluridine diacetate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.66g/cm3 |
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| Molecular Formula | C15H17BrN2O9 |
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| Molecular Weight | 449.21 |
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| Exact Mass | 448.01200 |
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| PSA | 142.99000 |
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| Index of Refraction | 1.578 |
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| InChIKey | OVWGEZUVGHETAU-HKUMRIAESA-N |
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| SMILES | CC(=O)OCC1OC(n2cc(Br)c(=O)[nH]c2=O)C(OC(C)=O)C1OC(C)=O |
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Synonyms
| [3,4-diacetyloxy-5-(5-bromo-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate |
