CAS 108238-41-1|3,6-Dihydroxyflavone

Introduction：Basic information about CAS 108238-41-1|3,6-Dihydroxyflavone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name3,6-Dihydroxyflavone
CAS Number108238-41-1Molecular Weight254.24
Density1.472g/cm3Boiling Point477.1ºC at 760 mmHg
Molecular FormulaC15H10O4Melting Point231-234ºC
MSDS/Flash Point186.2ºC

Names

Name3,6-dihydroxy-2-phenylchromen-4-one
SynonymMore Synonyms

3,6-Dihydroxyflavone BiologicalActivity

Description3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation[1].
Related CatalogSignaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer
References

[1]. Chang H, et al. 3,6-Dihydroxyflavone induces apoptosis in leukemia HL-60 cell via reactive oxygen species-mediated p38 MAPK/JNK pathway. Eur J Pharmacol. 2010;648(1-3):31-38.

Chemical & Physical Properties

Density1.472g/cm3
Boiling Point477.1ºC at 760 mmHg
Melting Point231-234ºC
Molecular FormulaC15H10O4
Molecular Weight254.24
Flash Point186.2ºC
Exact Mass254.05800
PSA70.67000
LogP2.87120
Vapour Pressure6.55E-10mmHg at 25°C
Index of Refraction1.712
InChIKeyXHLOLFKZCUCROE-UHFFFAOYSA-N
SMILESO=c1c(O)c(-c2ccccc2)oc2ccc(O)cc12
Water SolubilitySoluble in water.

Safety Information

WGK Germany3
HS Code2914400090

Customs

HS Code2914400090
Summary2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Synonyms

3,6-dihydroxy-flavone
2-phenyl-3,6-dihydroxy-4-benzopyrone
MFCD00143082
3,6-dihydroxy-2-phenyl-4-benzopyrone
6-Hydroxyflavonol
CAS 179057-20-6|3-(1H-Tetrazol-5-yl)benzyl alcohol
CAS 6665-66-3|5,6-dihydroxy-2-phenylchromen-4-one
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