Introduction：Basic information about CAS 370-98-9|N-Methyltyramine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Methyltyramine |
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| CAS Number | 370-98-9 | Molecular Weight | 151.21 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 270.9±15.0 °C at 760 mmHg |
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| Molecular Formula | C9H13NO | Melting Point | 121 - 126°C(lit.) |
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| MSDS | / | Flash Point | 119.7±11.0 °C |
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Names
| Name | N-methyltyramine |
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| Synonym | More Synonyms |
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N-Methyltyramine BiologicalActivity
| Description | N-Methyltyramine is a protoalkaloid that can be isolated from various plant species. N-Methyltyramine is an α2-adrenoreceptor antagonist. N-Methyltyramine enhances appetite and digestion of foods by stimulating gastrin and pancreatic secretions. N-Methyltyramine can relax mouse small intestinal smooth muscle and inhibits small intestinal propulsion[1][2]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Metabolic Disease |
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| References | [1]. Stohs SJ, et al. A review of the receptor binding and pharmacological effects of N-methyltyramine. Phytother Res. 2015 Jan;29(1):14-6. [2]. Ni J, et al. Effect of N-methyltyramine on the regulation of adrenergic receptors via enzymatic epinephrine synthesis for the treatment of gastrointestinal disorders. Biomed Pharmacother. 2019 Mar;111:1393-1398. |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 270.9±15.0 °C at 760 mmHg |
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| Melting Point | 121 - 126°C(lit.) |
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| Molecular Formula | C9H13NO |
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| Molecular Weight | 151.21 |
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| Flash Point | 119.7±11.0 °C |
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| Exact Mass | 151.099716 |
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| PSA | 32.26000 |
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| LogP | 0.86 |
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| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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| Index of Refraction | 1.541 |
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| InChIKey | AXVZFRBSCNEKPQ-UHFFFAOYSA-N |
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| SMILES | CNCCc1ccc(O)cc1 |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- SL8300000
- CHEMICAL NAME :
- Phenol, p-(2-methylaminoethyl)-
- CAS REGISTRY NUMBER :
- 370-98-9
- BEILSTEIN REFERENCE NO. :
- 2357129
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H13-N-O
- MOLECULAR WEIGHT :
- 151.23
- WISWESSER LINE NOTATION :
- QR D2M1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 780 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 106,341,1952
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 275 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 106,341,1952
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Safety Information
| Hazard Codes | C |
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| HS Code | 2922299090 |
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Customs
| HS Code | 2922299090 |
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| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| N-Methyltyramine |
| 4-Hydroxy-N-methylphenethylamine |
| Methyl-4-tyramine |
| Phenol, p-[2-(methylamino)ethyl]- |
| Phenol, 4-[2-(methylamino)ethyl]- |
| 4-[2-(Methylamino)ethyl]phenol |
| N-methyl-p-Tyramine |
| WIN 5582 |
| Tyramine,N-methyl |
| tyramine, N-methyl- |
| 4-(2-Methylamino-ethyl)-phenol |
