Introduction：Basic information about CAS 6681-18-1|(+)-Magnoflorine chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (+)-Magnoflorine chloride |
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| CAS Number | 6681-18-1 | Molecular Weight | 377.862 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C20H24ClNO4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Magnoflorine chloride |
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| Synonym | More Synonyms |
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(+)-Magnoflorine chloride BiologicalActivity
| Description | Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm[1]. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity[2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalResearch Areas >>Metabolic Disease |
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| References | [1]. Kim J, et al. Antifungal activity of magnoflorine against Candida strains. World J Microbiol Biotechnol. 2018 Oct 31;34(11):167. [2]. Haque MA, et al. Magnoflorine Enhances LPS-Activated Pro-Inflammatory Responses via MyD88-Dependent Pathways in U937 Macrophages. Planta Med. 2018 Nov;84(17):1255-1264. |
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Chemical & Physical Properties
| Molecular Formula | C20H24ClNO4 |
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| Molecular Weight | 377.862 |
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| Exact Mass | 377.139374 |
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| PSA | 58.92000 |
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| InChIKey | STVJLBTYWBXDBP-ZOWNYOTGSA-N |
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| SMILES | COc1ccc2c(c1O)-c1c(O)c(OC)cc3c1C(C2)[N+](C)(C)CC3.[Cl-] |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- CE0970000
- CHEMICAL NAME :
- 6a-alpha-Aporphinium, 1,11-dihydroxy-2,10-dimethoxy-6-methyl-, chloride
- CAS REGISTRY NUMBER :
- 6681-18-1
- LAST UPDATED :
- 198406
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H24-N-O4.Cl
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 19600 ug/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 7,135,1958
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Synonyms
| Corytuberine methochloride |
| Magnoflorine chloride |
| 1,11-dihydroxy-10-methoxynaphthacene-5,12-dione |
| (6aS)-1,11-Dihydroxy-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium chloride |
| 4H-Dibenzo[de,g]quinolinium, 5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-, chloride, (6aS)- (1:1) |
| 5,12-Naphthacenedione,1,11-dihydroxy-10-methoxy |
| Thalictrine chloride |
