Introduction：Basic information about CAS 569-90-4|Nepitrin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Nepitrin |
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| CAS Number | 569-90-4 | Molecular Weight | 478.403 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 844.7±65.0 °C at 760 mmHg |
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| Molecular Formula | C22H22O12 | Melting Point | / |
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| MSDS | / | Flash Point | 294.9±27.8 °C |
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Names
| Name | Nepetin-7-glucoside |
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| Synonym | More Synonyms |
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Nepitrin BiologicalActivity
| Description | Nepitrin, isolated from Scrophularia striata, possess significant anti-inflammatory and anti-arthritic activity[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Monsef-Esfahani HR, et al. Flavonoids, cinnamic acid and phenyl propanoid from aerial parts of Scrophularia striata. Pharm Biol. 2010 Mar;48(3):333-6. [2]. Agarwal OP, et al. The anti-inflammatory action of nepitrin, a flavonoid. Agents Actions. 1982 Jul;12(3):298-302. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 844.7±65.0 °C at 760 mmHg |
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| Molecular Formula | C22H22O12 |
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| Molecular Weight | 478.403 |
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| Flash Point | 294.9±27.8 °C |
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| Exact Mass | 478.111115 |
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| PSA | 199.51000 |
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| LogP | -0.68 |
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| Vapour Pressure | 0.0±3.3 mmHg at 25°C |
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| Index of Refraction | 1.715 |
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| InChIKey | DMXHXBGUNHLMQO-IWLDQSELSA-N |
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| SMILES | COc1c(OC2OC(CO)C(O)C(O)C2O)cc2oc(-c3ccc(O)c(O)c3)cc(=O)c2c1O |
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| Storage condition | 2-8℃ |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DJ3009500
- CHEMICAL NAME :
- 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)- 5-hydroxy-6- methoxy-
- CAS REGISTRY NUMBER :
- 569-90-4
- LAST UPDATED :
- 199403
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H22-O12
- MOLECULAR WEIGHT :
- 478.44
- WISWESSER LINE NOTATION :
- T66 BO EVJ CR CQ DQ& GQ HO1 IO- BT6OTJ CQ DQ EQ F1Q
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 794 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 19,201,1981
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Synonyms
| 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-5-hydroxy-6-methoxy- |
| nepitrin |
| 6-Methoxyluteolin 7-glucoside |
| 2-(3,4-Dihydroxyphenyl)-5-hydroxy-6-methoxy-4-oxo-4H-chromen-7-yl β-D-glucopyranoside |
| 6-Methoxyluteolin 7-O-glucoside |
