Introduction：Basic information about CAS 72-19-5|L-Threonine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].
Related Catalog
Research Areas >>OthersSignaling Pathways >>Others >>Others
References
[1]. Zhao H, et al. Increasing L-threonine production in Escherichia coli by engineering the glyoxylate shunt and the L-threonine biosynthesis pathway. Appl Microbiol Biotechnol. 2018 Jul;102(13):5505-5518.
Chemical & Physical Properties
Density
1.3±0.1 g/cm3
Boiling Point
345.8±32.0 °C at 760 mmHg
Melting Point
255ºC
Molecular Formula
C4H9NO3
Molecular Weight
119.119
Flash Point
162.9±25.1 °C
Exact Mass
119.058243
PSA
83.55000
LogP
-1.23
Vapour Pressure
0.0±1.7 mmHg at 25°C
Index of Refraction
1.507
InChIKey
AYFVYJQAPQTCCC-GBXIJSLDSA-N
SMILES
CC(O)C(N)C(=O)O
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
XO8590000
CHEMICAL NAME :
Threonine, L-
CAS REGISTRY NUMBER :
72-19-5
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H9-N-O3
MOLECULAR WEIGHT :
119.14
WISWESSER LINE NOTATION :
QY1&YZVQ -L
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3098 mg/kg
TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease
MUTATION DATA
TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81868 No. of Facilities: 53 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 750 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81868 No. of Facilities: 787 (estimated) No. of Industries: 3 No. of Occupations: 13 No. of Employees: 18524 (estimated) No. of Female Employees: 13980 (estimated)
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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