CAS 81279-39-2|5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

Introduction：Basic information about CAS 81279-39-2|5'-O-DMT-2'-O-iBu-N-Bz-Guanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
CAS Number81279-39-2Molecular Weight769.95800
Density1.25Boiling Point/
Molecular FormulaC41H51N5O8SiMelting Point/
MSDS/Flash Point/

Names

NameN-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
SynonymMore Synonyms

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine BiologicalActivity

Description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Thomas P Blaisdell, et al. Practical silyl protection of ribonucleosides. Org Lett. 2013 Sep 20;15(18):4710-3.

Chemical & Physical Properties

Density1.25
Molecular FormulaC41H51N5O8Si
Molecular Weight769.95800
Exact Mass769.35100
PSA159.31000
LogP6.87400
InChIKeyJMCNKJFOIJGYRG-CJEGOSRCSA-N
SMILESCOc1ccc(C(OCC2OC(n3cnc4c(=O)[nH]c(NC(=O)C(C)C)nc43)C(O[Si](C)(C)C(C)(C)C)C2O)(c2ccccc2)c2ccc(OC)cc2)cc1

Safety Information

Hazard CodesXi

Synonyms

5'-dimethoxytrityl 2'-tert-butyldimethyl silyl N-isobutyrylguanosine
(2)N-isobutyryl-5'O-dimetoxytrityl-3'O-tert-butyldimethylsilyl guanosine
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
5'-O-DMT-N-isobutyryl-2'-O-TBDMS-guanosine
N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tert-butyldimethylsilyl guanosine
N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
2-N-isobutyryl-2'-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)guanosine
5'-O-dimethoxytrityl-2'-O-tert-butyldimethylsilyl-N2-isobutyryl guanosine
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